A soluble aspartate aminopeptidase from dog kidney

Cheung, H.S.; Cushman, D.W.; Biochim. Biophys. Acta 242, 190-193 (1971)

 show all sequences of 3.4.11.7

Data extracted from this reference:

Localization
Localization Commentary Organism GeneOntology No. Textmining
cytosol
-
 Canis lupus familiaris 5829
-
microsome
-
 Canis lupus familiaris
-
-
Metals/Ions
Metals/Ions Commentary Organism Structure
Ca2+ activation; glutamate specific enzyme Canis lupus familiaris
Mn2+ activation; aspartate specific enzyme Canis lupus familiaris
Organism
Organism Primary Accession No. (UniProt) Commentary Textmining
Canis lupus familiaris
-
-
-
Purification (Commentary)
Commentary Organism
partial Canis lupus familiaris
Source Tissue
Source Tissue Commentary Organism Textmining
kidney
-
 Canis lupus familiaris
-
Substrates and Products (Substrate)
Substrates Commentary Substrates Literature (Substrates) Organism Products Commentary (Products) Literature (Products) Organism (Products) Reversibility
angiotensin I + H2O
-
 36026 Canis lupus familiaris Asp + Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
-
-
-
 ?
Asp-beta-naphthylamide + H2O dog kidney enzyme 3 times more active compared to Glu-beta-naphthylamide 36026 Canis lupus familiaris Asp + naphthylamine
-
-
-
 ?
Glu-beta-naphthylamide + H2O aminopeptidase A six times more active compared to Asp-beta-naphthylamide 36026 Canis lupus familiaris Glu + naphthylamine
-
-
-
 ?
Localization (protein specific)
Localization Commentary Organism GeneOntology No. Textmining
cytosol
-
 Canis lupus familiaris 5829
-
microsome
-
 Canis lupus familiaris
-
-
Metals/Ions (protein specific)
Metals/Ions Commentary Organism Structure
Ca2+ activation; glutamate specific enzyme Canis lupus familiaris
Mn2+ activation; aspartate specific enzyme Canis lupus familiaris
Purification (Commentary) (protein specific)
Commentary Organism
partial Canis lupus familiaris
Source Tissue (protein specific)
Source Tissue Commentary Organism Textmining
kidney
-
 Canis lupus familiaris
-
Substrates and Products (Substrate) (protein specific)
Substrates Commentary Substrates Literature (Substrates) Organism Products Commentary (Products) Literature (Products) Organism (Products) Reversibility
angiotensin I + H2O
-
 36026 Canis lupus familiaris Asp + Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
-
-
-
 ?
Asp-beta-naphthylamide + H2O dog kidney enzyme 3 times more active compared to Glu-beta-naphthylamide 36026 Canis lupus familiaris Asp + naphthylamine
-
-
-
 ?
Glu-beta-naphthylamide + H2O aminopeptidase A six times more active compared to Asp-beta-naphthylamide 36026 Canis lupus familiaris Glu + naphthylamine
-
-
-
 ?

See also following references to EC number 3.4.11.7 (sorted by year of publication):
No.1st authorPub
Med		titleorganimsjournalvolumepagesyearActivating CompoundApplicationCloned(Commentary)Crystallization (Commentary)EngineeringGeneral StabilityInhibitorsKM Value [mM]LocalizationMetals/IonsMolecular Weight [Da]Natural Substrates/ Products (Substrates)Organic Solvent StabilityOrganismOxidation StabilityPosttranslational ModificationPurification (Commentary)ReactionRenatured (Commentary)Source TissueSpecific Activity [micromol/min/mg]Storage StabilitySubstrates and Products (Substrate)SubunitsTemperature Optimum [°C]Temperature Range [°C]Temperature Stability [°C]Turnover Number [1/s]pH OptimumpH RangepH StabilityCofactorKi Value [mM]pI ValueIC50 ValueActivating Compound (protein specific)Application (protein specific)Cloned(Commentary) (protein specific)Cofactor (protein specific)Crystallization (Commentary) (protein specific)Engineering (protein specific)General Stability (protein specific)IC50 Value (protein specific)Inhibitors (protein specific)Ki Value [mM] (protein specific)KM Value [mM] (protein specific)Localization (protein specific)Metals/Ions (protein specific)Molecular Weight [Da] (protein specific)Natural Substrates/ Products (Substrates) (protein specific)Organic Solvent Stability (protein specific)Oxidation Stability (protein specific)Posttranslational Modification (protein specific)Purification (Commentary) (protein specific)Renatured (Commentary) (protein specific)Source Tissue (protein specific)Specific Activity [micromol/min/mg] (protein specific)Storage Stability (protein specific)Substrates and Products (Substrate) (protein specific)Subunits (protein specific)Temperature Optimum [°C] (protein specific)Temperature Range [°C] (protein specific)Temperature Stability [°C] (protein specific)Turnover Number [1/s] (protein specific)pH Optimum (protein specific)pH Range (protein specific)pH Stability (protein specific)pI Value (protein specific)ExpressionGeneral InformationGeneral Information (protein specific)Expression (protein specific)KCat/KM [mM/s]KCat/KM [mM/s] (protein specific)
717183KimStructural basis for the subst ...Streptococcus pneumoniaeBiochem. Biophys. Res. Commun.391431-4362010--11-----1---3--1-----11-------------1-1-------1-----1----11--------------
717392AsanoPurification and characterizat ...Glycine maxBiosci. Biotechnol. Biochem.74113-1182010------4---1--3--1--23-311-1--1-------------4----1----1-23-311-1--1--------
698879ClaperonIdentification of threonine 34 ...Mus musculusJ. Biol. Chem.28410618-106262009--1-3-48122--3--1--38-2----8----24----1--3--4248122----1-38-2----8----------
680004TonnaFunctional genetic variation i ...Homo sapiensGene41044-522008--1-15----1---4--------1--------------1--15------1----------1---------------
683509BodineauAminopeptidase A inhibitors as ...Mus musculus, Rattus norvegicusHeart Fail. Rev.13311-3192008-2----8--22--3-----2--2---------2---2------82--22------2--2---------------
683520BodineauOrally Active Aminopeptidase A ...Mus musculus, Rattus norvegicusHypertension511318-13252008-1----6--2---5-----19-3-----2-------1------6---2-------19-3-----2---------
683521PadiaConversion of renal angiotensi ...Rattus norvegicusHypertension51460-4652008-1----1-11-1-3-----7--1---------1---1------11-11-1-----7--1---------------
683799Llorens-CortesJacques Benoit lecture: the ne ...Rattus norvegicusJ. Neuroendocrinol.20279-2892008-1----4-1111-4-----1--1---------1---1------41-1111-----1--1---------------
683987Narvaez-VasquezTargeting and localization of ...Solanum lycopersicumPlanta227341-3512008--1-----3-1--4-----1-----------------1--------3-1------1------------------
696103ClaperonAsp218 participates with Asp21 ...Mus musculusBiochem. J.41637-462008--1-1-22122--3--1--2--2----2----1----1--1--212122----1-2--2----2----------
697164WuExpression of glutamyl aminope ...Rattus norvegicusCell Biol. Int.32748-7532008---------11--3-----4--21-----------------------11------4--21--------------
698166IshiiThe effect of recombinant amin ...Homo sapiensHorm. Metab. Res.40887-8912008--1-1---1----4--1-----2--------------1--1-----1------1----2---------------
699650de MotaHuman brain aminopeptidase A: ...Homo sapiens, Mus musculusJ. Neurochem.106416-4282008--1---12-12---6-----16--4--------------1-----12--12-------16--4---------------
701327OgawaExosome-like vesicles in Gloyd ...Gloydius blomhoffiToxicon51984-9932008--------1-1--4-----1--1-----------------------1-1------1--1---------------
680832TeuscherThe M18 aspartyl aminopeptidas ...Plasmodium falciparumJ. Biol. Chem.28230817-308262007-11---114212--4--1--12-311--411--8---11-----1184212----1-12-311--411--------
683508TsujimotoBiochemical and enzymatic prop ...Homo sapiens, Mus musculus, Rattus norvegicusHeart Fail. Rev.13285-291200733----6-336--4-----2--23----3------33------6--336------2--23----3---------
683558ZottaEnzymatic activities of lactic ...Lactobacillus curvatus, Lactobacillus paraplantarum, Lactobacillus pentosus, Lactobacillus plantarum, Leuconostoc mesenteroides, Weissella cibariaInt. J. Food Microbiol.115165-1722007-------------16------6-6-6---6---------------------------6-6-6---6---------
683663GotoAsparatic acid 221 is critical ...Homo sapiensJ. Biol. Chem.28237074-370812007--1-4-32611-1-3--1-----511--301---8----1--4--382611-1---1----511--301---------
684091OgawaCharacterization and cDNA clon ...Bothrops jararaca, Crotalus atrox, Gloydius blomhoffi, Gloydius blomhoffi brevicaudus, Trimeresurus flavoviridisToxicon491172-118120076-1---6------11--1--15-2-5---5------6-1-----6---------1-15-2-5---5---------
665010HarataLocalization of angiotensin II ...Homo sapiensFertil. Steril.86433-4392006-------------3-----4-----------------------------------4------------------
665723GotoEnzymatic properties of aminop ...Homo sapiensJ. Biol. Chem.28123503-235132006--1---21712-4-3-11--31-1411--611----7--1----721-712-4--11-31-1411--611--------
665903DijkmanExpression and effect of inhib ...Mus musculusJ. Histochem. Cytochem.54253-2622006-----------1-3-----6--2--------------------------1-----6--2---------------
681000SegarraAtrial angiotensinase activity ...Rattus norvegicusJ. Cardiovasc. Pharmacol.48117-1202006--------1--1-3-----54-1-----------------------1--1-----54-1---------------
681632BanegasBrain aminopeptidases and hype ...Rattus norvegicusJ. Renin Angiotensin Aldosterone Syst.7129-1342006-1----2----1-2-----1--1-------------1------2-----1-----1--1---------------
684050FaberLack of angiotensin II convers ...Mus musculusRegul. Pept.136130-1372006-----------1-3-----39-1-1---1--------------------1-----39-1-1---1---------
663814BanegasAngiotensinase activity is asy ...Rattus norvegicusBehav. Brain Res.156321-3262005--------1--1-5-----13--2-----------------------1--1-----13--2---------------
665836AgirregoitiaDistribution of peptidase acti ...Oncorhynchus mykiss, Rattus norvegicus, Sparus aurataJ. Comp. Physiol. B175433-4442005--------9----3-----336-3--3--------------------9--------336-3--3------------
666460Larrinaga-Subcellular distribution of me ...Homo sapiens, Rattus norvegicusNeurosci. Lett.383136-1402005--------122---2-----2--2-----2-----------------122-------2--2-----2---------
663456O-Wang-Aminopeptidase A ...Cavia porcellusHandbook of Proteolytic Enyzmes (2nd Ed)1299-3032004------10-211--1-----3--3-1---1--------------10--211------3--3-1---1---------
663609Iturrioz-Aminopeptidase inhibitors as a ...Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofaAminopetidases in Biology and Disease (Hooper, N.M.; Lendaechel, U., eds.) Springer2229-2502004-44-1-36-4818-4-4-4-30--368------------44--1--36--4818--4--30--368--------------
664275MitsuiRole of aminopeptidases in the ...Rattus norvegicusBiol. Pharm. Bull.27768-7712004------1----2-2--------3--------------------1-----2--------3---------------
665074Adang-Aminopeptidase A ...Mus musculusHandbook of Proteolytic Enzymes (2nd Edition)1299-3032004--1---10-2111-1--1--5--4-1---1--------1-----10--2111---1-5--4-1---1---------
665110Adang-Aminopeptidase A ...Rattus norvegicusHandbook of Proteolytic Enzymes (Barrett, J.; Rawlings, N.D.; Woessner, J.F., eds) Academic Press2nd. Ed. 1299-3032004------10-211--1-----5--3-1---1--------------10--211------5--3-1---1---------
665111Niven-Glutamyl aminopeptidase (Lacto ...Lactococcus lactis, Leuconostoc mesenteroides, Streptococcus agalactiae, Streptococcus mutans, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus suisHandbook of Proteolytic Enzymes (Barrett, J.; Rawlings, N.D.; Woessner, J.F., eds) Academic Press2nd. Ed. 1965-9682004------14371477-7--1-----17-7-2-7--------------14-371477---1----17-7-2-7---------
665570RozenfeldThe C-terminal domain of amino ...Mus musculusJ. Biol. Chem.27943285-432952004--1---1-32-2-3-3---3--411---1--------1-----1--32-2--3--3--411---1---------
666719Fournie-ZaluskiBrain renin-angiotensin system ...Mus musculus, Rattus norvegicusProc. Natl. Acad. Sci. USA1017775-77802004-2----4----2-6-----42-2-------------2------4-----2-----42-2---------------
654685RozenfeldContribution of molecular mode ...Mus musculusBiochemistry4214785-147932003--1-3-341----2-----2--1----4----12----1--3--31241--------2--1----4----------
654495OfnerThe C-terminal domain, but not ...Mus musculusBiochem. J.362191-1972002--1-2---4----3-1-------2-------------1--2-----4-----1------2--------------
656065RozenfeldContribution of molecular mode ...Mus musculusJ. Biol. Chem.27729242-292522002--1-5-1------2--1--2-----------------1--5--1---------1-2------------------
654587IturriozStudy of asparagine 353 in ami ...Mus musculusBiochemistry4014440-144482001--1-3-592----2-1---1--3----9----15----1--3--51592-----1--1--3----9----------
655731Healy-Regulation of aminopeptidase A ...Mus musculusInt. Congr. Ser.121855-652001--------11-1-1-----1--1-----------------------11-1-----1--1---------------
654568GeorgiadisPotent and selective inhibitio ...Mus musculusBiochemistry391152-11552000------61-----2--------1---------6----------661------------1---------------
654574IturriozHistidine 450 plays a critical ...Mus musculusBiochemistry393061-30682000--1-1-35-1---3--1-----1----5----15----1--1--3155-1-----1----1----5----------
656448DavidInvestigation of subsite prefe ...Mus musculusJ. Med. Chem.425197-52111999------27------2--------2---------29----------2729-------------2---------------
36030VazeuxProduction and properties of a ...Mus musculusEur. J. Biochem.254671-6781998--1-1---31---2-----11-1--------------1--1-----31-------11-1---------------
36034Llorens-CortesIdentification of metabolic pa ...Mus musculusC. R. Seances Soc. Biol. Fil.192607-6181998------1----1-2--------2--------------------1-----1--------2---------------
36029ZiniIdentification of metabolic pa ...Mus musculusProc. Natl. Acad. Sci. USA9311968-119731996------1----1-2--------2--------------------1-----1--------2---------------
36033Kinkowstrom-Aminopeptidase A from Phynchos ...Rhynchosciara americanaArch. Insect Biochem. Physiol.27301-3151994------1--11--1-----1--------1--------------1---11------1--------1---------
36031Yoshpe-BesanconPurification and characterizat ...Staphylococcus chromogenesEur. J. Biochem.211105-1101993------5--21--3--1---1-311---1-1------------5---21----1--1-311---1-1-------
665413FrickePeriplasmic aminopeptidases in ...Acinetobacter calcoaceticus, Pseudomonas aeruginosaJ. Basic Microbiol.33291-2991993--------2-2--5--2---1-2-----------------------2-2----2--1-2---------------
36032HerzigAngiotensinase A (aminopeptida ...Homo sapiensJ. Chromatogr.62573-821992-------2--2--4--1--22-1----------------------2--2----1-22-1---------------
36036ScherberichBiochemical and immunological ...Homo sapiensEur. J. Clin. Chem. Clin. Biochem.30663-6681992--------1----2--1--3--------------------------1------1-3------------------
36035Niven-Purification and characterizat ...Lactococcus lactisJ. Gen. Microbiol.1371207-12121991------43-11--1--1---1-511---1--------------4-3-11----1--1-511---1---------
35016PetrovicPurification and properties of ...Gallus gallusComp. Biochem. Physiol. B95589-5951990------61-21--3--1--11-311---1--------------6-1-21----1-11-311---1---------
36037WuMolecular cloning of the murin ...Mus musculusProc. Natl. Acad. Sci. USA87993-9971990--------2----4-----4--------------------------2--------4------------------
36011ExterkateEfficient implementation of co ...Lactococcus lactis subsp. cremorisAppl. Environ. Microbiol.531482-14861987--------1----1--------1-1---------------------1-----------1-1-------------
36012ExterkatePurification and some properti ...Lactococcus lactis subsp. cremorisAppl. Environ. Microbiol.53577-5831987------9-1-11-3--1---1-211-1----------------9--1-11---1--1-211-1-----------
35868LaluCharacterization of three amin ...Homo sapiensBiochim. Biophys. Acta873190-1971986------4--2---2-----2--2-----1--------------4---2-------2--2-----1---------
36013LaluPurification and partial chara ...Homo sapiensBiochim. Biophys. Acta789324-3331984------12-31--2--1--2113---1-1--------------1-2-31----1-2113---1-1---------
36015StewartProteins of the kidney microvi ...Sus scrofaBiochem. J.224549-5581984--------1----2-----1--------------------------1--------1------------------
36016DanielsenBiosynthesis of intestinal mic ...Sus scrofaBiochem. J.210389-3931983--------2----2-----3--------------------------2--------3------------------
36017Tobe-Synthesis and structure-activi ...Homo sapiensAgric. Biol. Chem.461865-18721982------1------1-----1-----------------------1-----------1------------------
36018MizutaniAminopeptidase A in human plac ...Homo sapiensBiochim. Biophys. Acta678168-1701981---------11--2--1--11-----1-1------------------11----1-11-----1-1---------
36019SterchiThe distribution of four pepti ...Homo sapiensBiochem. Soc. Trans.9130-1311981--------1----1-----1--------------------------1--------1------------------
36020FeracciEnzymatic and immunological pr ...Oryctolagus cuniculus, Sus scrofaBiochim. Biophys. Acta658148-1571981---------2---4-----2--------22-----------------2-------2--------22--------
36021DanielsenProteins of the kidney microvi ...Sus scrofaBiochem. J.189591-6031980------5-122--4--1--21241----11-------------5--122----1-21241----11--------
36022GorvelPurification and characterizat ...Oryctolagus cuniculusBiochim. Biophys. Acta615271-2741980--------1-1--3--1--2--11----------------------1-1----1-2--11--------------
36023BenajibaPurification and characterizat ...Sus scrofaEur. J. Biochem.107381-3881980--------1-2--4--1--2--1-----------------------1-2----1-2--1---------------
36024TobePurification by affinity chrom ...Sus scrofaBiochim. Biophys. Acta613459-4681980------61-31--2--1--21-1---2-1--------------6-1-31----1-21-1---2-1---------
36025DelVecchioCapillaries of the adrenal cor ...Rattus norvegicusBiochem. J.186605-6081980--------1----2-----1--------------------------1--------1------------------
36026CheungA soluble aspartate aminopepti ...Canis lupus familiarisBiochim. Biophys. Acta242190-1931971--------22---2--1--2--3-----------------------22-----1-2--3---------------
36027NagatsuPurification of aminopeptidase ...Homo sapiensBiochim. Biophys. Acta198255-2701970------21-31--2--1--21-1-----1--------------2-1-31----1-21-1-----1---------
36028GlennerA mammalian peptidase specific ...Rattus norvegicusNature1948671962------2------1-----2-----------------------2-----------2------------------