Ribonuclease H activity in cultured plant cells

Sawai, Y.; Sugano, N.; Tsukada, K.; Biochim. Biophys. Acta 518, 181-185 (1978)

 show all sequences of 3.1.26.4

Data extracted from this reference:

Metals/Ions
Metals/Ions Commentary Organism Structure
Mg2+
-
 Daucus carota
Organism
Organism Primary Accession No. (UniProt) Commentary Textmining
Daucus carota
-
 strain GD-2
-
Daucus carota GD-2
-
 strain GD-2
-
Source Tissue
Source Tissue Commentary Organism Textmining
root
-
 Daucus carota
-
Substrates and Products (Substrate)
Substrates Commentary Substrates Literature (Substrates) Organism Products Commentary (Products) Literature (Products) Organism (Products) Reversibility
More no degradation of single stranded RNA 134393 Daucus carota ?
-
-
-
-
RNA-DNA hybrid + H2O
-
 134393 Daucus carota ribonucleotide 5'-phosphomonoester
-
-
-
 ?
pH Optimum
pH Optimum Minimum pH Optimum Maximum Commentary Organism
8 9
-
 Daucus carota
Metals/Ions (protein specific)
Metals/Ions Commentary Organism Structure
Mg2+
-
 Daucus carota
Source Tissue (protein specific)
Source Tissue Commentary Organism Textmining
root
-
 Daucus carota
-
Substrates and Products (Substrate) (protein specific)
Substrates Commentary Substrates Literature (Substrates) Organism Products Commentary (Products) Literature (Products) Organism (Products) Reversibility
More no degradation of single stranded RNA 134393 Daucus carota ?
-
-
-
-
RNA-DNA hybrid + H2O
-
 134393 Daucus carota ribonucleotide 5'-phosphomonoester
-
-
-
 ?
pH Optimum (protein specific)
pH Optimum Minimum pH Optimum Maximum Commentary Organism
8 9
-
 Daucus carota

See also following references to EC number 3.1.26.4 (sorted by year of publication):
No.1st authorPub
Med		titleorganimsjournalvolumepagesyearActivating CompoundApplicationCloned(Commentary)Crystallization (Commentary)EngineeringGeneral StabilityInhibitorsKM Value [mM]LocalizationMetals/IonsMolecular Weight [Da]Natural Substrates/ Products (Substrates)Organic Solvent StabilityOrganismOxidation StabilityPosttranslational ModificationPurification (Commentary)ReactionRenatured (Commentary)Source TissueSpecific Activity [micromol/min/mg]Storage StabilitySubstrates and Products (Substrate)SubunitsTemperature Optimum [°C]Temperature Range [°C]Temperature Stability [°C]Turnover Number [1/s]pH OptimumpH RangepH StabilityCofactorKi Value [mM]pI ValueIC50 ValueActivating Compound (protein specific)Application (protein specific)Cloned(Commentary) (protein specific)Cofactor (protein specific)Crystallization (Commentary) (protein specific)Engineering (protein specific)General Stability (protein specific)IC50 Value (protein specific)Inhibitors (protein specific)Ki Value [mM] (protein specific)KM Value [mM] (protein specific)Localization (protein specific)Metals/Ions (protein specific)Molecular Weight [Da] (protein specific)Natural Substrates/ Products (Substrates) (protein specific)Organic Solvent Stability (protein specific)Oxidation Stability (protein specific)Posttranslational Modification (protein specific)Purification (Commentary) (protein specific)Renatured (Commentary) (protein specific)Source Tissue (protein specific)Specific Activity [micromol/min/mg] (protein specific)Storage Stability (protein specific)Substrates and Products (Substrate) (protein specific)Subunits (protein specific)Temperature Optimum [°C] (protein specific)Temperature Range [°C] (protein specific)Temperature Stability [°C] (protein specific)Turnover Number [1/s] (protein specific)pH Optimum (protein specific)pH Range (protein specific)pH Stability (protein specific)pI Value (protein specific)ExpressionGeneral InformationGeneral Information (protein specific)Expression (protein specific)KCat/KM [mM/s]KCat/KM [mM/s] (protein specific)
713673ReilingPurification and crystallizati ...Staphylococcus aureus subsp. aureusActa Crystallogr. Sect. F6779-822011--11-----2-1-3--1-----1--------------1-1-------2-1---1----1----------11---
714247JohnsonStructural basis of the RNase ...Homo sapiensBiochemistry503903-39122011---1---------1--------1----------------1------------------1---------------
714345RuhanenInvolvement of DNA ligase III ...Homo sapiensBiochim. Biophys. Acta18132000-20072011----1---2----3-----1--------------------1-----2--------1-------------11---
715036MiyashitaIdentification of the substrat ...Geobacillus stearothermophilusFEBS Lett.5852313-23172011--117--4-2-1-2--1---12-3-1---1--------1-17----4-2-1---1--12-3-1---1----11---
715580ReijnsThe structure of the human RNa ...Homo sapiensJ. Biol. Chem.28610530-105392011--119--7---1-4--------31---61--------1-19----7---1--------31---61----33-66
715581FigielThe structural and biochemical ...Homo sapiensJ. Biol. Chem.28610540-105502011---130---12-1-4--------2---1-1----------130-----12-1--------2---1-1----11---
716693TakanoStabilization by fusion to the ...Sulfolobus tokodaiiPLoS ONE6e162262011---12--------3------------1------------12---------------------1-----------
704328WatkinsStructural and functional char ...Mycobacterium tuberculosisJ. Bacteriol.1922878-28862010--111--------3--------2--------------1-11-----------------2---------------
707438KitamuraCharacterization of RNase HII ...Pyrococcus furiosusBiochem. J.426337-3442010--113--4-1---4--------21---6---------1-13----4-1----------21---6----------
708119HuA quadruplex-based, label-free ...Escherichia coliChemistry162605-26102010-1-----------1-----1----------------1------------------1------------------
709140ShabanThe structure of the mammalian ...Mus musculusJ. Biol. Chem.2853617-36242010---15--------4---1-----1---------------15------------------1--------------
714126ZhanCharacterization of a new RNas ...Sulfolobus tokodaiiBiochemistry (Moscow)75930-9372010----3-4--2---4--------1111--1-----------3--4---2----------1111--1----11---
714194RatcliffIdentification of residual str ...Chlorobaculum tepidum, Thermus thermophilusBiochemistry495167-51752010--2-8--2-----5--2-1-------2----------2--8----2-------21-------2-----------
714962JongrujaThe N-terminal hybrid binding ...Thermotoga maritimaFEBS J.2774474-44892010--1-2--1-4-1-2------2-411---1--------1--2----1-4-1------2-411---1----11---
715367Le LazStructure-specific nuclease ac ...Pyrococcus abyssiJ. Bacteriol.1923689-36982010--1---11-1-1-3--------1-1--12--------1-----1-1-1-1--------1-1--12----11-11
716001LiuSynthesis of 2,4-propylene-bri ...Homo sapiensJ. Org. Chem.757112-71282010----1-14--2---1----------1---1-----------1--14---2------------1---1---------
716211SuzukiAn upstream open reading frame ...Mus musculusMol. Cell. Biol.305123-51342010--1-----3----1---------1-------------1--------3------------1---------11---
716222RychlikCrystal structures of RNase H2 ...Thermotoga maritimaMol. Cell40658-6702010--115----2-1-2--------4-----21-------1-15------2-1--------4-----21---22---
716995BeilhartzHIV-1 ribonuclease H: structur ...Escherichia coli, Homo sapiensViruses2900-9262010---21----1-2-5--------22---------------21------1-2--------22---------11---
693579FujiDerivatives of 5-nitrofuran-2- ...Homo sapiensJ. Med. Chem.521380-13872009------1------1--------1-----------2-------21--------------1---------------
694046Bigotlmo1273, a novel gene involved ...Listeria monocytogenes EGD-eMicrobiology155891-9022009----1--------8--------------------------1---------------------------------
707499RatcliffStructure, stability, and fold ...Chlorobaculum tepidumBiochemistry485890-58982009--111--------3------------2----------1-11---------------------2-----------
708487RohmanDestabilization of psychrotrop ...Shewanella oneidensis MR-1FEBS J.276603-6132009---15--------3------5-1---6------------15---------------5-1---6-----------
709259SchmittThermal and mechanical multist ...Escherichia coliJ. Chem. Phys.1312351012009-------------2----1-----------------------------------1-------------------
709285RostaArtificial reaction coordinate ...Bacillus haloduransJ. Comput. Chem.301634-16412009-------------1---1--------------------------------------------------------
709522ConnellThe folding trajectory of RNas ...Escherichia coliJ. Mol. Biol.391450-4602009----2--------3----1---------------------2-------------1-------------------
709523ConnellA single mutation at residue 2 ...Escherichia coliJ. Mol. Biol.391461-4702009----1--------3--------------------------1---------------------------------
709895FluiterFilling the gap in LNA antisen ...Homo sapiensMol. Biosyst.5838-8432009-------------1-----1--1--------------------------------1--1---------------
710142ChonContributions of the two acces ...Homo sapiensNucleic Acids Res.3796-1102009--1-6----2---7--1-----31----1--------3--6------6-----3----93----3---------
710143KauffmannImprovement of RNA secondary s ...Escherichia coliNucleic Acids Res.37e1212009-1-----------1-----1----------------1------------------1------------------
691677PallanInsights into RNA/DNA hybrid r ...Bacillus haloduransCell Cycle72562-25692008---1-----1-1-4--------1----------------1-------1-1--------1---------------
691767MoriguchiSpermine moiety attached to th ...Escherichia coliChem. Pharm. Bull.561259-12632008-------------1------------------------------------------------------------
692746De VivoPhosphodiester cleavage in rib ...Bacillus haloduransJ. Am. Chem. Soc.13010955-109622008----2----1---3--------1-----------------2------1----------1---------------
693672ZhouThe high-resolution NMR struct ...Thermus thermophilusJ. Mol. Biol.384531-5392008----1-----2--3--1------1--1-------------1-------2----1-----1--1-----------
694458SalonDerivatization of DNAs with se ...Bacillus haloduransNucleic Acids Res.367009-70182008---11--------1-------------------------11---------------------------------
677389LoukachevitchCrystallization and preliminar ...Escherichia coliActa Crystallogr. Sect. F6384-882007--11---------1--------1--------------1-1------------------1---------------
678280HoncharenkoComparison of the RNase H clea ...Escherichia coliBiochemistry465635-56462007-------7-1---1-----1--7-11-61----------------7-1-------1--7-11-61---------
678503PatureauInduction of RNase H activity ...Homo sapiensBioconjugate Chem.18421-43020071--------1-1-1--------3-1---1------1-----------1-1--------3-1---1---------
681431BastockThe pH-dependence of the Esche ...Escherichia coliJ. Mol. Biol.368421-4332007--1----1-1---4--11----1----111-------1-------1-1-----1----1----111--------
681692YarringtonMn2+ suppressor mutations and ...Saccharomyces cerevisiaeJ. Virol.819004-90122007----10-1--1-1-6--------1-1---1-----------10--1---1-1--------1-1---1---------
681805LiangBiochemical characterization a ...Chlamydophila pneumoniaeMicrobiology153787-7932007--1-1----1---5--------3-1-1-11-------1--1------1----------3-1-1-11--------
682020LimaThe positional influence of th ...Homo sapiensMol. Pharmacol.7173-822007------1------1--------2-1---1--------------1--------------2-1---1---------
682021LimaHuman RNase H1 discriminates b ...Homo sapiensMol. Pharmacol.7183-912007--1----1-1-1-1--1-----3-1---1--------1-------1-1-1---1----3-1---1---------
682205HouA method for HLA genotyping us ...Chlamydophila pneumoniaeOligonucleotides17433-4432007---------1---4------1-2-1---1------------------1--------1-2-1---1---------
664755NowotnyStepwise analyses of metal ion ...Bacillus halodurans, Homo sapiensEMBO J.251924-19332006--2211----5-1-2--11----321---1--------2-211------5-1---1----321---1---------
664911ChonIdentification of RNase HII fr ...Escherichia coli, Shewanella sp.FEBS J.2732264-22752006--1--4-3-121--6--1---4-61222-22-------1---4---3-121----1--4-61222-22--------
664916KochiwaStage-specific expression of C ...Caenorhabditis elegansFEBS J.273420-4292006--1----1-2---4--1--14-2--------------1-------1-2-----1-14-2---------------
666070ChonCrystal structure and structur ...Geobacillus stearothermophilusJ. Mol. Biol.356165-1782006--115----2-1-4---1--9-511---2--------1-15------2-1------9-511---2---------
666879LivesayConserved quantitative stabili ...Escherichia coli, Thermus thermophilusProteins62130-1432006-------2---2-2---2----22--2------------------2---2--------22--2-----------
677553TangControlling RNA digestion by R ...Homo sapiensAngew. Chem.453523-3526200611-----1---1-1--------3-1-1-1------11--------1---1--------3-1-1-1---------
663628FangDetermination of ribonuclease ...Escherichia coliAnal. Chem.776528-65342005-------1-----2-----1-11-1--11----------------1---------1-11-1--11---------
666037TsunakaIdentification of single Mn2+ ...Escherichia coliJ. Mol. Biol.3451171-11832005--113----1---3--11-------------------1-13------1-----1--------------------
666288MisraA type II ribonuclease H from ...Leishmania donovani, Leishmania majorMol. Biochem. Parasitol.143135-1452005-22-----3--2-5-22--4--22------------22--------3--2--22-4--22--------------
666490BudihasSelective inhibition of HIV-1 ...Escherichia coli, Homo sapiensNucleic Acids Res.331249-12562005------16------6--------2---------2----------162-------------2---------------
664359ChonGene cloning and biochemical c ...Geobacillus stearothermophilusBiosci. Biotechnol. Biochem.682138-21472004--1---3--41--5--1-----31111-1----1---1-----3---41----1----31111-1--1------
665555LimaStructural Requirements at the ...Homo sapiensJ. Biol. Chem.27936317-363262004--1----------1--11----2-1---1--------1---------------1----2-1---1---------
654694TsunakaDispensability of glutamic aci ...Escherichia coliBiochemistry423366-33742003--1-9-1--3---3---1--6-1-1---1--------1--9--1---3--------6-1-1---1---------
654714LaiMetal ion binding and enzymati ...Methanocaldococcus jannaschiiBiochemistry42785-7912003--1-4--2-3---3--11----3----211-------1--4----2-3-----1----3----211--------
655784MangosEfficient RNase H-directed cle ...Escherichia coli, Homo sapiensJ. Am. Chem. Soc.125654-6612003---------4-2-4--------8-2--22------------------4-2--------8-2--22---------
656122LimaHuman RNase H1 activity is reg ...Homo sapiensJ. Biol. Chem.27814906-1491220032-1-5-1--3-1-1--1---1-3-1---1------2-1--5--1---3-1---1--1-3-1---1---------
655447ten AsbroekThe involvement of human ribon ...Homo sapiensEur. J. Biochem.269583-5922002--1--12-22-1-3--1--61-2-1---1--------1---1-2--22-1---1-61-2-1---1---------
657193RydbergExcision of misincorporated ri ...Escherichia coli, Homo sapiens, Pyrococcus furiosus, Saccharomyces cerevisiaeProc. Natl. Acad. Sci. USA9916654-166592002----1----8---8--2--3--9-4---4-----------1------8-----2-3--9-4---4---------
656012BhagwatBacteriophage T4 RNase H remov ...Enterobacteria phage T4J. Biol. Chem.27628516-285242001-----------2-3--------6-1---1--------------------2--------6-1---1---------
656489ChapadosStructural biochemistry of a t ...Archaeoglobus fulgidusJ. Mol. Biol.307541-5562001--114--5-2-1-3--11----511--41--------1-14----5-2-1---1----511--41---------
657146GromihaFactors influencing the stabil ...Thermus thermophilusPrep. Biochem. Biotechnol.31103-1122001-----1-------2---------1--1--------------1-----------------1--1-----------
657287MuroyaCatalytic center of an archaea ...Thermococcus kodakarensisProtein Sci.10707-7142001--116--8-4---3--11----1-1---1--------1-16----8-4-----1----1-1---1---------
654408KobilFunctional analysis of the dom ...Trypanosoma bruceiBiochem. Biophys. Res. Commun.270336-3422000--1-1-1-12---3--11----11-------------1--1--1--12-----1----11--------------
654569HiranoEnhancement of the enzymatic a ...Thermus thermophilusBiochemistry3913285-132942000--1-7--8-1---5--1---1-1-2--91--------1--7----8-1-----1--1-1-2--91---------
655904OhtaniCharacterization of ribonuclea ...Escherichia coliJ. Biochem.127895-8992000--1---21-51--4--1-1-2-121---11-------1-----2-1-51----11-2-121---11--------
657218HarukiEfficient cleavage of RNA at h ...Escherichia coli, Thermus thermophilusProtein Eng.13881-8862000--2-6--------6---1--2-415-3-2--------2--6---------------2-415-3-2---------
657310GoedkenDivalent metal cofactor bindin ...Escherichia coliProtein Sci.91914-19212000--1111-1-1---3---1-----11---1--------1-111---1-1-----------11---1---------
134402NakaiSequence-specific cleavage of ...Escherichia coliFEBS Lett.33967-721994-1--1--------1--------1-------------1---1-----------------1---------------
134404HuangMetallobiochemistry of the mag ...Escherichia coliEur. J. Biochem.219253-2601994---------2---3--------1------------------------2----------1---------------
134405DaboraEquilibrium unfolding of Esche ...Escherichia coliProtein Sci.31401-14081994----1--------3--1-----1-----------------1------------1----1---------------
134406FrankPurification and characterizat ...Homo sapiensNucleic Acids Res.225247-52541994------62-21--3--1--21-2-----11-------------6-2-21----1-21-2-----11--------
134408CazenaveCharacterization and subcellul ...Xenopus laevisJ. Biol. Chem.26925185-251921994--------3-2--4-----3--11----------------------3-2------3--11--------------
134411CazenaveCharacterization of ribonuclea ...Oryctolagus cuniculus, Triticum aestivumBiochimie75113-1221993------4--3---5-----4--2--------------------4---3-------4--2---------------
134400KanayaA hybrid ribonuclease H. A nov ...Escherichia coliJ. Biol. Chem.2678492-84981992----1--------3--------1-----------------1-----------------1---------------
134403KanayaExpression, purification, and ...Escherichia coli, Thermus thermophilusJ. Biol. Chem.26710184-101921992--1---24-21--5--1-----211-421--------1-----2-4-21----1----211-421---------
134409EderRibonuclease H from K562 human ...Homo sapiensJ. Biol. Chem.2666472-64791991------1--411-4--1--21-51----1--------------1---411---1-21-51----1---------
134080ItayaIsolation and characterization ...Escherichia coliProc. Natl. Acad. Sci. USA878587-85911990--1-------11-3--1-1-113--------------1----------11---11-113---------------
134373RongOn the molecular weight and su ...Bos taurusBiochemistry29383-3891990----------2--2-----1--11------------------------2------1--11--------------
134401YangExpression, purification, and ...Escherichia coliJ. Biol. Chem.26513553-135591990---1---------3--1---1-1----------------1-------------1--1-1---------------
134412VonwirthCalf thymus ribonuclease H IIa ...Bos taurusExperientia46319-3211990---------22--2-----1--21-----------------------22------1--21--------------
134377KanayaOverproduction and preliminary ...Escherichia coliJ. Biol. Chem.26411546-115491989---1---------3--1-----1----------------1-------------1----1---------------
134078WintersbergerThree ribonucleases H and a re ...Saccharomyces cerevisiaeBiochim. Biophys. Acta951322-3291988---------2---2--------2------------------------2----------2---------------
134383KarwanIn addition to RNase H(70) two ...Saccharomyces cerevisiaeJ. Biol. Chem.26314970-149771988---------11--3--11--1-2------------------------11----1--1-2---------------
134381KarwanRibonuclease H(70) from Saccha ...Saccharomyces cerevisiaeProc. Natl. Acad. Sci. USA835919-59231986-------------3--------2-----------------------------------2---------------
134382KarwanYeast ribonuclease H(70) cleav ...Saccharomyces cerevisiaeFEBS Lett.206189-1921986-------------2--------1-----------------------------------1---------------
134068Crouch-Ribonuclease H ...Bos taurus, Escherichia coli, Homo sapiens, Mus musculus, Rattus norvegicus, Saccharomyces cerevisiae, Xenopus laevisCold Spring Harbor Monogr. Ser.14211-2541982------2-3--2-7-----6--9--------------------2--3--2-----6--9---------------
134372BuesenThe subunit structure of calf ...Bos taurusJ. Biol. Chem.2577106-71081982-------------2-----1--12-------------------------------1--12--------------
134380CheriathundamPurification and properties of ...Saccharomyces cerevisiaeArch. Biochem. Biophys.219110-1201982------1--13--2------1-3---1---2------------1---13-------1-3---1---2-------
134392KitaharaPurification and properties of ...Gallus gallusJ. Biochem.92855-86419821-----7--22--1--1--11-1-----2------1-------7---22----1-11-1-----2---------
134391DirksenSelective inhibition of RNase ...Escherichia coliJ. Biol. Chem.25611569-115731981------1------2--------2--------------------1--------------2---------------
134371BuesenPurification, subunit structur ...Bos taurusJ. Biol. Chem.2559434-944319801-----1-131--4--1--11-11-----------1-------1--131----1-11-11--------------
134390SawaiMultiple forms of ribonuclease ...Rattus norvegicusJ. Biochem.86757-76419791-----2-22---2--1--21-1------------1-------2--22-----1-21-1---------------
134394SawaiTwo ribonucleases H from cultu ...Daucus carotaJ. Biochem.851301-130819792-----1--22--3--1--1--2-----2------2-------1---22----1-1--2-----2---------
134399CathalaIsolation and characterization ...Mus musculusJ. Biol. Chem.2547353-736119791-----82-52--1--1--1--11-----------1-------8-2-52----1-1--11--------------
134370StavrianopoulosSimplified method for purifica ...Bos taurusProc. Natl. Acad. Sci. USA754140-41441978------2--31--2--1--11-1--------------------2---31----1-11-1---------------
134387TashiroRibonuclease H from rat liver. ...Rattus norvegicusJ. Biochem.84385-39319781-----2-321--3--1--2111-----1------1-------2--321----1-2111-----1---------
134388TashiroRibonuclease H from rat liver. ...Rattus norvegicusJ. Biochem.84395-4021978--------3-2--3--1--2--2-----------------------3-2----1-2--2---------------
134389SawaiTwo ribonuclease H activities ...Rattus norvegicusBiochem. Biophys. Res. Commun.84313-3211978------1-211--2--1--2--1-----1--------------1--211----1-2--1-----1---------
134393SawaiRibonuclease H activity in cul ...Daucus carotaBiochim. Biophys. Acta518181-1851978---------1---3-----1--2-----1------------------1-------1--2-----1---------
134076Wyers-Role of DNA-RNA hybrids in euk ...Saccharomyces cerevisiaeEur. J. Biochem.69377-3831976-------------1--1-----1------------------------------1----1---------------
134077Wyers-Role of DNA-RNA hybrids in euk ...Saccharomyces cerevisiaeEur. J. Biochem.69385-39519761--------21--1--1-----11-----------1-----------21----1----11--------------
134369StavrianopoulosRibonuclease H of calf thymus: ...Bos taurusProc. Natl. Acad. Sci. USA731087-10911976------2--3---3-----1--3--------------------2---3-------1--3---------------
134396TashiroMultiple forms of nuclear ribo ...Tetrahymena pyriformisEur. J. Biochem.65123-1301976------1-22---4--1-----1-----1--------------1--22-----1----1-----1---------
134386RoewekampPurification and characteristi ...Rattus norvegicusEur. J. Biochem.43405-4131974------3-221--1--1--1--21----11-------------3--221----1-1--21----11--------
134395CooperMultiple ribonuclease H activi ...Mesocricetus auratusFEBS Lett.4538-431974------3--3---1-----1-11-----6--------------3---3-------1-11-----6---------
134397BanksA ribonuclease H from Ustilago ...Ustilago maydisEur. J. Biochem.47499-50719742-----1--31--2--1---1-1-1---1------2-------1---31----1--1-1-1---1---------
134367HaberkernStudies on a calf thymus ribon ...Bos taurusBiochemistry122389-23951973------61121--1--1--11-2--------------------6-1121----1-11-2---------------
134368StavrianopoulosPurification and properties of ...Bos taurusProc. Natl. Acad. Sci. USA701959-19631973------4--32--1-----11-3--------------------4---32------11-3---------------
134374HenryA hybridase from Escherichia c ...Escherichia coliBiochem. Biophys. Res. Commun.50603-6111973-------------1--1---1-1------------------------------1--1-1---------------
134375MillerRibonuclease H (hybrid) in Esc ...Escherichia coliJ. Biol. Chem.2482621-26241973------1---1--2--1-----1---1----------------1----1----1----1---1-----------
134376BerkowerIsolation and characterization ...Escherichia coliJ. Biol. Chem.2485914-592119731-----1--1---1--1-----3-----11-----1-------1---1-----1----3-----11--------
134398O'CuinnTwo ribonuclease H activities ...Mus musculusBiochim. Biophys. Acta32478-851973-------------2--1--11-1-----22----------------------