Reduced fructosamine-3-kinase activity and its mRNA in human distal colorectal carcinoma

Notarnicola, M.; Caruso, M.G.; Tutino, V.; Guerra, V.; Frisullo, S.; Altomare, D.F.; Misciagna, G.; Genes Nutr. 5, 257-262 (2010)

show all sequences of 2.7.1.171

Data extracted from this reference:

Organism
Organism Primary Accession No. (UniProt) Commentary Textmining
Homo sapiens
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Source Tissue
Source Tissue Commentary Organism Textmining
colon fructosamine-3-kinase is a functionally active enzyme in human colon tissue, without significant differences between normal mucosa and cancer. The mean level of fructosamine-3-kinase mRNA is significantly lower in cancer than in the corresponding normal colorectal mucosa. The colorectal tumors located on the left side show lower levels of both enzymatic activity and mRNA fructosamine-3-kinase than tumors located in the right side of colon Homo sapiens
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Source Tissue (protein specific)
Source Tissue Commentary Organism Textmining
colon fructosamine-3-kinase is a functionally active enzyme in human colon tissue, without significant differences between normal mucosa and cancer. The mean level of fructosamine-3-kinase mRNA is significantly lower in cancer than in the corresponding normal colorectal mucosa. The colorectal tumors located on the left side show lower levels of both enzymatic activity and mRNA fructosamine-3-kinase than tumors located in the right side of colon Homo sapiens
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See also following references to EC number 2.7.1.171 (sorted by year of publication):
No.1st authorPub
Med
titleorganimsjournalvolumepagesyearActivating CompoundApplicationCloned(Commentary)Crystallization (Commentary)EngineeringGeneral StabilityInhibitorsKM Value [mM]LocalizationMetals/IonsMolecular Weight [Da]Natural Substrates/ Products (Substrates)Organic Solvent StabilityOrganismOxidation StabilityPosttranslational ModificationPurification (Commentary)ReactionRenatured (Commentary)Source TissueSpecific Activity [micromol/min/mg]Storage StabilitySubstrates and Products (Substrate)SubunitsTemperature Optimum [°C]Temperature Range [°C]Temperature Stability [°C]Turnover Number [1/s]pH OptimumpH RangepH StabilityCofactorKi Value [mM]pI ValueIC50 ValueActivating Compound (protein specific)Application (protein specific)Cloned(Commentary) (protein specific)Cofactor (protein specific)Crystallization (Commentary) (protein specific)Engineering (protein specific)General Stability (protein specific)IC50 Value (protein specific)Inhibitors (protein specific)Ki Value [mM] (protein specific)KM Value [mM] (protein specific)Localization (protein specific)Metals/Ions (protein specific)Molecular Weight [Da] (protein specific)Natural Substrates/ Products (Substrates) (protein specific)Organic Solvent Stability (protein specific)Oxidation Stability (protein specific)Posttranslational Modification (protein specific)Purification (Commentary) (protein specific)Renatured (Commentary) (protein specific)Source Tissue (protein specific)Specific Activity [micromol/min/mg] (protein specific)Storage Stability (protein specific)Substrates and Products (Substrate) (protein specific)Subunits (protein specific)Temperature Optimum [°C] (protein specific)Temperature Range [°C] (protein specific)Temperature Stability [°C] (protein specific)Turnover Number [1/s] (protein specific)pH Optimum (protein specific)pH Range (protein specific)pH Stability (protein specific)pI Value (protein specific)ExpressionGeneral InformationGeneral Information (protein specific)Expression (protein specific)KCat/KM [mM/s]KCat/KM [mM/s] (protein specific)
707094van SchaftingenEnzymatic repair of Amadori pr ...Homo sapiens, Mus musculusAmino Acids421143-11502012----1------2-4--1--1--2-----------------1--------2---1-1--2---------1111--
708589NotarnicolaReduced fructosamine-3-kinase ...Homo sapiensGenes Nutr.5257-2622010-------------3-----2-----------------------------------2------------------
707061PascalEffects of fructosamine-3-kina ...Mus musculusAm. J. Physiol. Endocrinol. Metab.298E586-5962009-------------4-----1---1-------------------------------1---1---------11---
708421MohasA polymorphism within the fruc ...Homo sapiensExp. Clin. Endocrinol. Diabetes118209-2122009----1--------3--------------------------1---------------------------------
710172CarusoGene expression of fructosamin ...Homo sapiensOncology7372-752008-------------1------------------------------------------------------1--1--
707098KrauseA convenient HPLC assay for th ...Homo sapiensAnal. Bioanal. Chem.3862019-20252006-1---------1-2-----1--2-1---1-------1------------1-----1--2-1---1---------
707426Veiga da-CunhaIncreased protein glycation in ...Mus musculusBiochem. J.399257-2642006-----------1-1--------1--------------------------1--------1----------22---
708287DelpierreVariability in erythrocyte fru ...Homo sapiensDiabetes Metab.3231-392005-------------3-----2-----------------------------------2------------------
707351ConnerThe expression of the genes fo ...Homo sapiensBiochem. Biophys. Res. Commun.323932-9362004-------------2-----3-----------------------------------3------------1--1--
708296CollardA mammalian protein homologous ...Homo sapiens, Mus musculusDiabetes522888-28952004--1---44---2-5--1--8--7-----------4--1----44-4---2---1-8--7---------------
708979DelpierrreIdentification of fructosamine ...Homo sapiensJ. Biol. Chem.27927613-276202004-----------1-3-----1--2--------------------------1-----1--2---------------
708981DelplanqueTissue distribution and evolut ...Gallus gallus, Mus musculus, Rattus norvegicus, Sus scrofaJ. Biol. Chem.27946606-466132004-----------3-12--3--16--6-2---3--------------------3---3-16--6-2---3---1--1--
707456BrownModulation of in vivo 3-deoxyg ...Rattus norvegicusBiochem. Soc. Trans.311433-14372003-1----1----1-1-----1--2---------1---1------11----1-----1--2---------1--1--
707420DelpierreFructosamine 3-kinase is invol ...Homo sapiensBiochem. J.365801-8082002--1---112--2-3--1--3--31-------------1-----1-12--2---1-3--31--------------
708295SzwergoldHuman fructosamine-3-kinase: p ...Homo sapiensDiabetes502139-21472001-------4---1-3--11-21-611---1----------------4---1---1-21-611---1---------
708294DelpierreIdentification, cloning, and h ...Homo sapiens, Mus musculusDiabetes491627-16342000--2----11---2-6--2--2--1522---2--------2-------11---2---2-2--1522---2----22---