Cytosolic branched chain aminotransferase (BCATc) mRNA is up-regulated in restricted brain areas of BDNF transgenic mice

Castellano, S.; Macchi, F.; Scali, M.; Huang, J.Z.; Bozzi, Y.; Brain Res. 1108, 12-18 (2006)

 show all sequences of 2.6.1.42

Data extracted from this reference:

Cloned(Commentary)
Commentary Organism
expressed in transgenic Mus musculus expressing the brain-derived neurotrophic factor cDNA under the control of the alpha-calcium/calmodulin-dependent kinase II promoter Rattus norvegicus
Localization
Localization Commentary Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-
Organism
Organism Primary Accession No. (UniProt) Commentary Textmining
Rattus norvegicus
-
-
-
Source Tissue
Source Tissue Commentary Organism Textmining
brain
-
 Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates Commentary Substrates Literature (Substrates) Organism Products Commentary (Products) Literature (Products) Organism (Products) Reversibility
L-isoleucine + 2-oxoglutarate
-
 672847 Rattus norvegicus 3-methyl-2-oxopentanoate + L-glutamate
-
-
-
 ?
L-leucine + 2-oxoglutarate
-
 672847 Rattus norvegicus 4-methyl-2-oxopentanoate + L-glutamate
-
-
-
 ?
L-valine + 2-oxoglutarate
-
 672847 Rattus norvegicus 3-methyl-2-oxobutanoate + L-glutamate
-
-
-
 ?
Cloned(Commentary) (protein specific)
Commentary Organism
expressed in transgenic Mus musculus expressing the brain-derived neurotrophic factor cDNA under the control of the alpha-calcium/calmodulin-dependent kinase II promoter Rattus norvegicus
Localization (protein specific)
Localization Commentary Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-
Source Tissue (protein specific)
Source Tissue Commentary Organism Textmining
brain
-
 Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates Commentary Substrates Literature (Substrates) Organism Products Commentary (Products) Literature (Products) Organism (Products) Reversibility
L-isoleucine + 2-oxoglutarate
-
 672847 Rattus norvegicus 3-methyl-2-oxopentanoate + L-glutamate
-
-
-
 ?
L-leucine + 2-oxoglutarate
-
 672847 Rattus norvegicus 4-methyl-2-oxopentanoate + L-glutamate
-
-
-
 ?
L-valine + 2-oxoglutarate
-
 672847 Rattus norvegicus 3-methyl-2-oxobutanoate + L-glutamate
-
-
-
 ?

See also following references to EC number 2.6.1.42 (sorted by year of publication):
No.1st authorPub
Med		titleorganimsjournalvolumepagesyearActivating CompoundApplicationCloned(Commentary)Crystallization (Commentary)EngineeringGeneral StabilityInhibitorsKM Value [mM]LocalizationMetals/IonsMolecular Weight [Da]Natural Substrates/ Products (Substrates)Organic Solvent StabilityOrganismOxidation StabilityPosttranslational ModificationPurification (Commentary)ReactionRenatured (Commentary)Source TissueSpecific Activity [micromol/min/mg]Storage StabilitySubstrates and Products (Substrate)SubunitsTemperature Optimum [°C]Temperature Range [°C]Temperature Stability [°C]Turnover Number [1/s]pH OptimumpH RangepH StabilityCofactorKi Value [mM]pI ValueIC50 ValueActivating Compound (protein specific)Application (protein specific)Cloned(Commentary) (protein specific)Cofactor (protein specific)Crystallization (Commentary) (protein specific)Engineering (protein specific)General Stability (protein specific)IC50 Value (protein specific)Inhibitors (protein specific)Ki Value [mM] (protein specific)KM Value [mM] (protein specific)Localization (protein specific)Metals/Ions (protein specific)Molecular Weight [Da] (protein specific)Natural Substrates/ Products (Substrates) (protein specific)Organic Solvent Stability (protein specific)Oxidation Stability (protein specific)Posttranslational Modification (protein specific)Purification (Commentary) (protein specific)Renatured (Commentary) (protein specific)Source Tissue (protein specific)Specific Activity [micromol/min/mg] (protein specific)Storage Stability (protein specific)Substrates and Products (Substrate) (protein specific)Subunits (protein specific)Temperature Optimum [°C] (protein specific)Temperature Range [°C] (protein specific)Temperature Stability [°C] (protein specific)Turnover Number [1/s] (protein specific)pH Optimum (protein specific)pH Range (protein specific)pH Stability (protein specific)pI Value (protein specific)ExpressionGeneral InformationGeneral Information (protein specific)Expression (protein specific)KCat/KM [mM/s]KCat/KM [mM/s] (protein specific)
701495TremblayThe 1.9 A structure of the bra ...Mycobacterium tuberculosisActa Crystallogr. Sect. F651071-10772009--11------1--4--1------1-------1-----111--------1----1-----1--------------
705527HutsonRedox regulation and trapping ...Homo sapiensMethods Mol. Biol.476135-1482009--------2----3-----2-----------1------1-------2--------2------------------
705733CaballeroDocking and quantitative struc ...Homo sapiensMol. Divers.13493-5002009--------2--3-3--------3--------1------1-------2--3--------3---------------
706387GaoA branched-chain aminotransfer ...Nicotiana benthamianaPlanta230611-6232009--1-----1-13-6-----5--3--------1-----11-------1-13-----5--3----------11---
702237ConwayRegulatory control of human cy ...Homo sapiensBiochemistry475465-54792008----71--2----2--1--1--3----32---1------1-71----2------1-1--3----32--------3131
671131ChenPurification, crystallization ...Deinococcus radioduransActa Crystallogr. Sect. F63492-4942007--11------2--3--1-----31-------1-----111--------2----1----31--------------
671284SaitoPurification of branched-chain ...Helicobacter pylori, Helicobacter pylori NCTC 11637Amino Acids33445-4492007-------4--3--5--1-----1722---1--1-2----1------6--3----1----1723---2--2------
673846CastellanoExpression of cytosolic branch ...Mus musculusGene Expr. Patterns7485-4902007--------2----4-----9--2--------1------1-------2--------9--2---------------
675509Garcia-EspinosaWidespread neuronal expression ...Rattus norvegicusJ. Neurochem.1001458-14682007--------1----3-----9--------------------------1--------9------------------
672589HuThe design and synthesis of hu ...Homo sapiensBioorg. Med. Chem. Lett.162337-23402006------20-1----3-----1--1-----------20-------2020--1--------1--1---------------
672765MagnusMonitoring and modeling of the ...Corynebacterium glutamicumBiotechnol. Prog.221071-10832006-----------1-3--------2--------------------------1--------2---------------
672847CastellanoCytosolic branched chain amino ...Rattus norvegicusBrain Res.110812-182006--1-----3----6-----3--3--------------1--------3--------3--3---------------
673758LillyThe effect of increased branch ...Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4742FEMS Yeast Res.6726-7432006-11----------4--------2--------1----111-------------------2---------------
674728YennawarHuman mitochondrial branched c ...Homo sapiensJ. Biol. Chem.28139660-396712006--113---2----31-1-----4----20---1-----1113-----2----1-1----4----20----------
675563BrosnanBranched-chain amino acids: en ...Homo sapiensJ. Nutr.136207S-211S2006------1-2----2-----2--2--------1------1----1--2--------2--2---------------
676421SchusterBranched-chain aminotransferas ...Arabidopsis thalianaPlant Cell182664-26792006--1----3--1--4--1--3--5--------------1-------3--1----1-3--5---------------
676462KnopfThe female-specific Cs-ACS1G g ...Cucumis sativusPlant Cell Physiol.471217-12282006-------------3------------------------------------------------------------
677188MalatrasiA branched-chain amino acid am ...Hordeum vulgareTheor. Appl. Genet.113965-9762006--1-------1--6-----1--2--------1-----11---------1------1--2---------------
660763BondarInvolvement of a branched-chai ...Yarrowia lipolyticaAppl. Environ. Microbiol.714585-45912005-6-----------4--------1-------------6---------------------1---------------
661792BeckBranched-chain fatty acid bios ...Staphylococcus carnosusFEMS Microbiol. Lett.24337-442005----3--------2--------------------------3---------------------------------
662423GotoStructural determinants for br ...Homo sapiensJ. Biol. Chem.28037246-372562005---1--1-4----3-----------------14-----11---14-4---------------------------
662753Perez-VillasenorMitochondrial branched chain a ...Rattus norvegicusLife Sci.78334-3392005-------31----3-1---32-31---------------------31-----1--32-31--------------
663104SchusterThe mitochondrial branched-cha ...Arabidopsis thalianaPlant Mol. Biol.57241-2542005--------5--1-3-----3--4-----------------------5--1-----3--4---------------
660663SweattBranched-chain amino acid cata ...Rattus norvegicusAm. J. Physiol.286E64-762004-------------4-----9-----------------------------------9------------------
661400VenosBranched-chain amino acid amin ...Mycobacterium tuberculosisBMC Microbiol.4392004--1---410-----6------10-6---------8----1-----4810----------10-6---------------
661957ThagePurification and characterizat ...Lactobacillus paracaseiJ. Appl. Microbiol.96593-6022004-1----8---1--5--1---1-721---2-------1------8----1----1--1-721---2---------
662522SweattBranched-chain amino acids and ...Rattus norvegicusJ. Comp. Neurol.477360-3702004--------4----4-----4--------------------------4--------4------------------
640042ConwayHuman mitochondrial branched c ...Homo sapiensBiochim. Biophys. Acta164761-652003---1----2--2-3--------4--------1------11------2--2--------4---------------
640043CooperHuman mitochondrial and cytoso ...Homo sapiensBiochem. Pharmacol.65181-1922003--1---622----1--------51-------1-----11----6-22-----------51--------------
640044GotoCrystal structures of branched ...Escherichia coli, Rattus norvegicusBiochemistry423725-37332003---1-------6-5--------7--------2------21---------6--------7---------------
640039CooperA continuous 96-well plate spe ...Homo sapiens, Rattus norvegicusAnal. Biochem.308100-1052002--1-----4--2-2--1--4--3--------------1--------4--2---1-4--3---------------
640040DieboldThe branched-chain amino acid ...Arabidopsis sp.Plant Physiol.129540-5502002--1-----4--3-13--------4--------------7--------4--3--------4---------------
640041MadsenCloning and inactivation of a ...Staphylococcus carnosusAppl. Environ. Microbiol.684007-40142002-33--------2-1--------4--------3----333----------2--------4---------------
640033EdenInvolvement of branched-chain ...Saccharomyces cerevisiaeAppl. Microbiol. Biotechnol.55296-3002001-----------3-4--------4--------------------------3--------4---------------
640034FaureBranched-chain amino acid amin ...Ovis ariesJ. Nutr.1311528-15342001--------2--3-2-----3--3-----------------------2--3-----3--3---------------
640035LinAn isoform of branched-chain a ...Homo sapiens, Saccharomyces cerevisiaeJ. Biol. Chem.27648196-482052001--1-----3----6-----1--1--------------2--------3--------1--1---------------
640036OkadaStructures of Escherichia coli ...Escherichia coliBiochemistry407453-74632001---1---------3---------1-------1------11-------------------1--------------
640037TorresOntogeny and subcellular local ...Rattus norvegicusEur. J. Biochem.2686132-61392001--1-----3-33-3-----121-3--------------1--------3-33-----121-3---------------
640038YennawarThe structure of human mitocho ...Homo sapiensActa Crystallogr. Sect. D57506-5152001---1--1-3--2-4--1-----41-------1------11---1--3--2---1----41--------------
640027AtilesGene cloning, sequencing, and ...Lactococcus lactis, Lactococcus lactis LM0230Appl. Environ. Microbiol.662325-23292000--1-----2--3-6------5-6--------------1--------2--3------5-6---------------
640028BonfilsSheep cytosolic branched-chain ...Ovis ariesBiochim. Biophys. Acta1494129-1362000--1-----2-13-9-----5--3--------1-----61-------2-13-----5--3---------------
640029ConwayMammalian branched-chain amino ...Homo sapiens, Rattus norvegicusMethods Enzymol.324355-3652000--2-----4--5-2--1---2-7--------------2--------4--5---1--2-7---------------
640030KagamiyamaBranched-chain amino-acid amin ...Escherichia coli, Escherichia coli W3110Methods Enzymol.324103-1132000--11---14---3-3--1---1-91---7---1-----111-----14---3---1--1-91---7----------
640031SchadewaldtDetermination of branched-chai ...Homo sapiens, Rattus norvegicusMethods Enzymol.32423-322000-------312----2--1--7--9----------------------312------1-7--9---------------
640032YvonCharacterization and role of t ...Lactococcus lactisAppl. Environ. Microbiol.66571-5772000-11--19---13-6--1---131711-1-1--1----121--1-9----13---1--131711-1-1---------
640026FaurePurification and cloning of th ...Ovis ariesEur. J. Biochem.259104-1111999--1-----2-13-6--1--31-31-------------2--------2-13---1-31-31--------------
640024EdenCharacterization of a branched ...Schizosaccharomyces pombeYeast14189-1941998--1-----2-1--6-----------------------1--------2-1-------------------------
640025HutsonRole of branched-chain aminotr ...Homo sapiens, Rattus norvegicusJ. Neurochem.71863-8741998------2-4--5-4--1--5--8--------------------2--4--5---1-5--8---------------
640022KispalMitochondrial and cytosolic br ...Saccharomyces cerevisiaeJ. Biol. Chem.27124458-244641996--1-----2----2--------4--------------1--------4-----------4---------------
640023SchadewaldtCoupled enzymatic assay for es ...Bos taurus, Rattus norvegicusAnal. Biochem.23865-711996------16---1-2--1--2--2-----11--1----------116---1---1-2--2-----11--------
640020KandaPurification and properties of ...Brevibacillus brevisJ. Nutr. Sci. Vitaminol.4151-601995------47--13-3--1---14131----1--1------1----4-7--13---1--14131----1---------
640021Schadewaldt-Human branched-chain L-amino a ...Homo sapiensAmino Acids9147-1601995--------2--1-1-----2--35-----11-1------1-------2--1-----2--35-----11--------
640019HallBranched chain aminotransferas ...Rattus norvegicusJ. Biol. Chem.2683092-30981993------5-3-13-4--1--1111191-------------------5--3-13---1-1111191--------------
33983XingCharacterization of enzymes of ...Methanococcus aeolicus, Methanococcus maripaludis, Methanococcus voltaeJ. Bacteriol.1732086-20921991----------110-8--4---1-16-------------------------110---4--1-16---------------
640017WallinPurification of branched chain ...Rattus norvegicus, Rattus norvegicus Sprague-DawleyJ. Biol. Chem.2656019-60241990-----1--2-13-4--1--21131-----------------1----2-13---1-21131--------------
640015FeildAmino acid sequence of Salmone ...Salmonella enterica subsp. enterica serovar TyphimuriumBiochemistry285306-53101989--11------13-4--1-----31-------1-----111--------13---1----31--------------
640016KamitoriCrystallization and preliminar ...Escherichia coliJ. Biochem.105671-6721989---1-------3-2--1-----3----------------1---------3---1----3---------------
640011Bode-Purification and properties of ...Candida maltosaBiochem. Physiol. Pflanz.183417-4241988--------3-12-1--1-----4-----2-----------------3-12---1----4-----2---------
640012InoueBranched-chain amino acid amin ...Escherichia coli, Escherichia coli W3110J. Biochem.104777-7841988--1----14--23-5--1---1-71------21-----11------14--23---1--1-71------2-------
640013KidoPancreatic branched-chain-amin ...Canis lupus familiaris, Homo sapiens, Rattus norvegicusMethods Enzymol.166275-2811988-----31430--63-3--3--42-73--3-5------------3-14-30--63---3-42-73--3-5---------
640014KorpelaPurification of branched-chain ...Rattus norvegicus, Sus scrofaMethods Enzymol.166269-2741988--------4-1--2--1--1011-2----1--2------2-------4-1----1-1011-2----1---------
640009CooperGlutamate-branched-chain amino ...Rattus norvegicus, Sus scrofaMethods Enzymol.11371-731985--------2--4-2--1--10--13-----------------------2--4---1-10--13---------------
640010KorpelaAffinity chromatography of B6- ...Sus scrofaJ. Chromatogr.318333-34119851----1----1--1--1--11111-----------1-----1------1----1-11111--------------
640008Kawagishi-Two isozymes of branched-chain ...Macaca sp.Shika Kiso Igakkai Zasshi26947-9521984-------------1--1--1---------------------------------1-1------------------
640007Shiio-Amino acid aminotransferase in ...[Brevibacterium] flavumAgric. Biol. Chem.462967-29771982------16---1-1--1-----8--------------------1-6---1---1----8---------------
640006Aarnes-Branched chain amino acid amin ...Hordeum vulgareZ. Pflanzenphysiol.10281-891981-----138--13-1--1--41130-----2------------1-3-8--13---1-41130-----2---------
640005Lee-PengTransaminase B from Escherichi ...Escherichia coliJ. Bacteriol.139339-3451979--1----7--23-2--1---2-61-------------1-------7--23---1--2-61--------------
640004Koide-Branched chain amino acid amin ...Pseudomonas sp.Agric. Biol. Chem.411171-117719771-----25---2-1--1---1-35---------3--1-------235---2---1--1-35---------------
640002MonnierTransaminase B from Escherichi ...Escherichia coliBiochimie58663-6751976----------11-3--1-----21-----11-----------------11---1----21-----11-------
640003Tachiki-Purification and characterizat ...Gluconobacter oxydansAgric. Biol. Chem.402187-219219767-----415--23-1--1---1-14-1-1-1-13---7--3----4-15--23---1--1-14-1-1-1-1-------
640001WakitaA branched-chain amino acid am ...Entodinium sp.J. Protozool.22281-2851975------24--13-2--1--1--3-----1--1------1----2-4--13---1-1--3-----1---------
640000Lipscomb-Molecular weight, subunit stru ...Salmonella enterica subsp. enterica serovar TyphimuriumBiochemistry132071-20771974------1---1--1--1------1-------------------1----1----1-----1--------------
639998CollinsBranded chain amino acid amino ...Neurospora crassaArch. Biochem. Biophys.155184-1931973--------2-23-1--1---2-11-----2-----------------2-23---1--2-11-----2---------
639999Tachiki-Separation of L-leucine-pyruva ...Gluconobacter oxydansAgric. Biol. Chem.371439-14481973-----------3-1--1---1-4-----1--------------------3---1--1-4-----1---------
639997AkiTransaminase of branched chain ...Sus scrofaJ. Biochem.65539-54419691------42-13-1--1--31-71----2--1---1--1------42-13---1-31-71----2---------
639996AkiTransaminases of branched chai ...Rattus norvegicus, Sus scrofaBiochim. Biophys. Acta159276-28419682------46--7-2--1--21-11-----1--2---2--2------46--7---1-21-11-----1---------
639993IchiharaTransaminase of branched chain ...Rattus norvegicus, Sus scrofaJ. Biochem.59160-1691966-----1445--6-2--1--81-11--11-1-12------2--1-4-45--6---1-81-11--11-1-1-------
639994TaylorLeucine aminotransferase. 3. A ...Sus scrofaJ. Biol. Chem.2414406-441019661-----9------1--1--112-------------1-------9---------1-112----------------
639995TaylorLeucine aminotransferase. II. ...Sus scrofaJ. Biol. Chem.2414396-440519661-----4---13-1--1--11212-----1111---1--1----4----13---1-11212-----111-------
639992RudmanTransamination in Escherichia ...Escherichia coliJ. Biol. Chem.200591-6041953-----------1-1--------11--------1------1----------1--------11---------------