GM3 alpha2,8-sialyltransferase (GD3 synthase): protein characterization and sub-Golgi location in CHO-K1 cells

Daniotti, J.L.; Martina, J.A.; Giraudo, C.G.; Zurita, A.R.; Maccioni, H.J.F.; J. Neurochem. 74, 1711-1720 (2000)

show all sequences of 2.4.99.8

Data extracted from this reference:

Cloned(Commentary)
Commentary Organism
expression in CHO-K1 cells Gallus gallus
Molecular Weight [Da]
Molecular Weight [Da] Molecular Weight Maximum [Da] Commentary Organism
45000
-
SDS-polyacrylamide-gel electrophoresis in the presence of beta-mercaptoethanol Gallus gallus
95000
-
SDS-polyacrylamide-gel electrophoresis in the absence of beta-mercaptoethanol Gallus gallus
Organism
Organism Primary Accession No. (UniProt) Commentary Textmining
Gallus gallus
-
-
-
Cloned(Commentary) (protein specific)
Commentary Organism
expression in CHO-K1 cells Gallus gallus
Molecular Weight [Da] (protein specific)
Molecular Weight [Da] Molecular Weight Maximum [Da] Commentary Organism
45000
-
SDS-polyacrylamide-gel electrophoresis in the presence of beta-mercaptoethanol Gallus gallus
95000
-
SDS-polyacrylamide-gel electrophoresis in the absence of beta-mercaptoethanol Gallus gallus


See also following references to EC number 2.4.99.8 (sorted by year of publication):
No.1st authorPub
Med
titleorganimsjournalvolumepagesyearActivating CompoundApplicationCloned(Commentary)Crystallization (Commentary)EngineeringGeneral StabilityInhibitorsKM Value [mM]LocalizationMetals/IonsMolecular Weight [Da]Natural Substrates/ Products (Substrates)Organic Solvent StabilityOrganismOxidation StabilityPosttranslational ModificationPurification (Commentary)ReactionRenatured (Commentary)Source TissueSpecific Activity [micromol/min/mg]Storage StabilitySubstrates and Products (Substrate)SubunitsTemperature Optimum [°C]Temperature Range [°C]Temperature Stability [°C]Turnover Number [1/s]pH OptimumpH RangepH StabilityCofactorKi Value [mM]pI ValueIC50 ValueActivating Compound (protein specific)Application (protein specific)Cloned(Commentary) (protein specific)Cofactor (protein specific)Crystallization (Commentary) (protein specific)Engineering (protein specific)General Stability (protein specific)IC50 Value (protein specific)Inhibitors (protein specific)Ki Value [mM] (protein specific)KM Value [mM] (protein specific)Localization (protein specific)Metals/Ions (protein specific)Molecular Weight [Da] (protein specific)Natural Substrates/ Products (Substrates) (protein specific)Organic Solvent Stability (protein specific)Oxidation Stability (protein specific)Posttranslational Modification (protein specific)Purification (Commentary) (protein specific)Renatured (Commentary) (protein specific)Source Tissue (protein specific)Specific Activity [micromol/min/mg] (protein specific)Storage Stability (protein specific)Substrates and Products (Substrate) (protein specific)Subunits (protein specific)Temperature Optimum [°C] (protein specific)Temperature Range [°C] (protein specific)Temperature Stability [°C] (protein specific)Turnover Number [1/s] (protein specific)pH Optimum (protein specific)pH Range (protein specific)pH Stability (protein specific)pI Value (protein specific)ExpressionGeneral InformationGeneral Information (protein specific)Expression (protein specific)KCat/KM [mM/s]KCat/KM [mM/s] (protein specific)
699089RuckhaeberleGene expression of ceramide ki ...Homo sapiensJ. Cancer Res. Clin. Oncol.1351005-10132009-1-----------3-----2----------------1------------------2------------2112--
684918GuIdentification and analysis of ...Homo sapiensBiochem. Biophys. Res. Commun.37067-712008--113--8-----1--------1--------------1-13----8------------1---------------
686288BentropMolecular evolution and expres ...Danio rerioDev. Dyn.237808-8182008----1--------4-----2--------------------1--------------2------------------
686977WillisCharacterization of the alpha- ...Escherichia coli, Neisseria meningitidisGlycobiology18177-1862008--2-2--4-1---5--------4-----1--------2--2----4-1----------4-----1---------
686980ChengMultifunctionality of Campylob ...Campylobacter jejuniGlycobiology18686-6972008--1-1--------4-----------------------1--1---------------------------------
689168BernardoElimination of GD3 synthase im ...Mus musculusNeurobiol. Aging301777-17912008-1--1--------5-----2----------------1---1--------------2------------------
689234ZitmanNeuromuscular synaptic functio ...Mus musculusNeuroscience156885-8972008----1--------1--------------------------1---------------------------------
689982KangDisialoganglioside GD3 synthas ...Homo sapiensProteomics83317-33282008--1-1--------2-----------------------1--1---------------------------------
702889Harduin-LepersEvolutionary history of the al ...Danio rerioBMC Evol. Biol.82582008-------------11-----4-----------------------------------19------------------
681899RimoldiMolecular cloning and expressi ...Xenopus laevis, Xenopus (Silurana) tropicalisMol. Cell. Biochem.301143-1532007--2----------7-----8---1-------------3-----------------15---1--------------
684842KangDisialoganglioside GD3 increas ...Homo sapiensBiochem. Biophys. Res. Commun.356418-4232007-1--1--------2-----1----------------1---1--------------1------------------
685329Kang-Expression of the human CMP-Ne ...Homo sapiensBiochim. Biophys. Acta1769622-6302007-------------1-----1-----------------------------------1------------------
700260FreibergerBiochemical characterization o ...Neisseria meningitidisMol. Microbiol.651258-12752007-11-6--12-11-4--1---1-311---1-------11--6----12-11---1--1-311---1---------
674638WangRoles for UDP-GlcNAc 2-epimera ...Homo sapiensJ. Biol. Chem.28127016-270282006-----------1-2-----1--1--------------------------1-----1--1---------------
677920KimMolecular mechanisms involved ...Homo sapiensBiochem. Biophys. Res. Commun.3441057-10642006-----------1-3-----5--1--------------------------1-----5--1---------------
680035KangTranscriptional regulation of ...Homo sapiensGlycobiology16375-3892006--1----------3-----1--1--------------1-----------------1--1---------------
682104GarigeChronic ethanol consumption do ...Rattus norvegicusNeurochem. Int.49312-3182006-------------3-----2-----------------------------------2------------------
658937KamimuraDifferential enhancing effects ...Homo sapiensInt. J. Oncol.26337-3442005-1-----------1-----2----------------1------------------2------------------
677856YamadaGD3 synthase gene found expres ...Mus musculusArch. Oral Biol.50393-3992005-------------2-----5-----------------------------------5------------------
658675TomassiniCalnexin suppresses GD3 syntha ...Homo sapiensFASEB J.181553-15552004--------2----2--------------------------------2---------------------------
658743HaOverexpression of GD3 synthase ...Homo sapiensFEBS Lett.568183-1872004-1-----------2-----1----------------1------------------1------------------
657819ArdailThe mitochondria-associated en ...Rattus norvegicusBiochem. J.3711013-10192003--------1----1-----1--------------------------1--------1------------------
489590DaniottiGM3 alpha2,8-sialyltransferase ...Gallus gallusJ. Neurochem.741711-17202000--1-------2--3-----------------------1----------2-------------------------
639663BieberichEffect of N-glycosylation on t ...Mus musculus, Rattus norvegicusJ. Neurochem.742359-23642000--2-----1----3-----------------------2--------1---------------------------
639661WatanabeThe molecular cloning and expr ...Rattus norvegicusJ. Biochem.1201020-10271996--1----------5-----6-----------------1-----------------6------------------
639660KojimaEnzymatic activity of a develo ...Mus musculusFEBS Lett.3601-41995--1----------1--------1--------------1--------------------1---------------
636888FreischutzActivities of five different s ...Oreochromis mossambicus, Rattus norvegicus, Rattus norvegicus Sprague-DawleyJ. Neurochem.621965-19731994--------2----3--1--2--------------------------2------1-2------------------
639659SasakiExpression cloning of a GM3-sp ...Homo sapiensJ. Biol. Chem.26915950-159561994--1----------3-----1-----------------1-----------------1------------------
637737IberSubstrate specificity of alpha ...Rattus norvegicusEur. J. Biochem.195115-12019911-------1----1-----1--1-1-1--------1----------1--------1--1-1-1-----------
637742TrincheraSub-Golgi distribution in rat ...Rattus norvegicusJ. Biol. Chem.26518242-1824719901-----4--2---1-----1--2-----1------1-------4---2-------1--2-----1---------
638784GuPurification to homogeneity of ...Rattus norvegicusBiochem. Biophys. Res. Commun.166387-39319903-------1-1--2--1--71-1-1----------3----------1-1----1-71-1-1-------------
587166KleinSubstrate specificity of GM2 a ...Rattus norvegicusEur. J. Biochem.167417-4241987--------2--1-3-----21-6-1---------------------2--1-----21-6-1-------------
587167YusufOligosialogangliosides inhibit ...Rattus norvegicusBiol. Chem. Hoppe-Seyler368455-46219872-----4-2----1-----1--1-1----------2-------4--2--------1--1-1-------------
637736BusamGanglioside biosynthesis in ra ...Rattus norvegicusEur. J. Biochem.16023-3019861-----9221---2-----1--2-1---1------1-------9-221-------1--2-1---1---------
636879HigashiBiosynthesis in vitro of disia ...Gallus gallusJ. Biol. Chem.260824-82819855-----231----2-----1--2-1----------5-------2-31--------1--2-1-------------
638788EpplerGanglioside biosynthesis in ra ...Rattus norvegicusBiochim. Biophys. Acta619332-3431980------15-2----2-----1--1-1------------------15--2--------1--1-1-------------
639650EpplerGanglioside biosynthesis in ra ...Rattus norvegicusBiochim. Biophys. Acta619318-33119803-----2221---2-1---11-2-1---1------3-------2-221----1--11-2-1---1---------
639653YoheIn vitro biosynthesis of an is ...Gallus gallusJ. Biol. Chem.255608-61319803-----311----1-----1--2-1---1------3-------3-11--------1--2-1---1---------
637739FishmanButyrate-induced glycolipid bi ...Homo sapiensArch. Biochem. Biophys.172618-6261976-------------1-----1--1--------------------------------1--1---------------