D-Asparatate oxidase in the thyroid gland

Jaroszewicz, L.; Enzyme 20, 80-89 (1975)

 show all sequences of 1.4.3.1

Data extracted from this reference:

Inhibitors
Inhibitors Commentary Organism Structure
KCN
-
 Sus scrofa
Localization
Localization Commentary Organism GeneOntology No. Textmining
mitochondrion
-
 Sus scrofa 5739
-
Natural Substrates/ Products (Substrates)
Natural Substrates Organism Commentary (Nat. Sub.) Natural Products Commentary (Nat. Pro.) Organism (Nat. Pro.) Reversibility
D-aspartate + H2O + O2 Sus scrofa
-
 oxaloacetate + NH3 + H2O2
-
-
 ?
Organism
Organism Primary Accession No. (UniProt) Commentary Textmining
Sus scrofa
-
-
-
Purification (Commentary)
Commentary Organism
-
 Sus scrofa
Source Tissue
Source Tissue Commentary Organism Textmining
thyroid gland
-
 Sus scrofa
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Commentary Organism
0.4
-
-
 Sus scrofa
Substrates and Products (Substrate)
Substrates Commentary Substrates Literature (Substrates) Organism Products Commentary (Products) Literature (Products) Organism (Products) Reversibility
D-aspartate + H2O + O2
-
 391726 Sus scrofa oxaloacetate + NH3 + H2O2
-
-
-
 ?
D-aspartate + H2O + O2
-
 391726 Sus scrofa oxaloacetate + NH3 + H2O2
-
 391726 Sus scrofa ?
D-glutamate + H2O + O2
-
 391726 Sus scrofa 2-oxoglutarate + NH3 + H2O2
-
-
-
 ?
pH Optimum
pH Optimum Minimum pH Optimum Maximum Commentary Organism
8.7
-
-
 Sus scrofa
Cofactor
Cofactor Commentary Organism Structure
FAD
-
 Sus scrofa
Cofactor (protein specific)
Cofactor Commentary Organism Structure
FAD
-
 Sus scrofa
Inhibitors (protein specific)
Inhibitors Commentary Organism Structure
KCN
-
 Sus scrofa
Localization (protein specific)
Localization Commentary Organism GeneOntology No. Textmining
mitochondrion
-
 Sus scrofa 5739
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates Organism Commentary (Nat. Sub.) Natural Products Commentary (Nat. Pro.) Organism (Nat. Pro.) Reversibility
D-aspartate + H2O + O2 Sus scrofa
-
 oxaloacetate + NH3 + H2O2
-
-
 ?
Purification (Commentary) (protein specific)
Commentary Organism
-
 Sus scrofa
Source Tissue (protein specific)
Source Tissue Commentary Organism Textmining
thyroid gland
-
 Sus scrofa
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Commentary Organism
0.4
-
-
 Sus scrofa
Substrates and Products (Substrate) (protein specific)
Substrates Commentary Substrates Literature (Substrates) Organism Products Commentary (Products) Literature (Products) Organism (Products) Reversibility
D-aspartate + H2O + O2
-
 391726 Sus scrofa oxaloacetate + NH3 + H2O2
-
-
-
 ?
D-aspartate + H2O + O2
-
 391726 Sus scrofa oxaloacetate + NH3 + H2O2
-
 391726 Sus scrofa ?
D-glutamate + H2O + O2
-
 391726 Sus scrofa 2-oxoglutarate + NH3 + H2O2
-
-
-
 ?
pH Optimum (protein specific)
pH Optimum Minimum pH Optimum Maximum Commentary Organism
8.7
-
-
 Sus scrofa

See also following references to EC number 1.4.3.1 (sorted by year of publication):
No.1st authorPub
Med		titleorganimsjournalvolumepagesyearActivating CompoundApplicationCloned(Commentary)Crystallization (Commentary)EngineeringGeneral StabilityInhibitorsKM Value [mM]LocalizationMetals/IonsMolecular Weight [Da]Natural Substrates/ Products (Substrates)Organic Solvent StabilityOrganismOxidation StabilityPosttranslational ModificationPurification (Commentary)ReactionRenatured (Commentary)Source TissueSpecific Activity [micromol/min/mg]Storage StabilitySubstrates and Products (Substrate)SubunitsTemperature Optimum [°C]Temperature Range [°C]Temperature Stability [°C]Turnover Number [1/s]pH OptimumpH RangepH StabilityCofactorKi Value [mM]pI ValueIC50 ValueActivating Compound (protein specific)Application (protein specific)Cloned(Commentary) (protein specific)Cofactor (protein specific)Crystallization (Commentary) (protein specific)Engineering (protein specific)General Stability (protein specific)IC50 Value (protein specific)Inhibitors (protein specific)Ki Value [mM] (protein specific)KM Value [mM] (protein specific)Localization (protein specific)Metals/Ions (protein specific)Molecular Weight [Da] (protein specific)Natural Substrates/ Products (Substrates) (protein specific)Organic Solvent Stability (protein specific)Oxidation Stability (protein specific)Posttranslational Modification (protein specific)Purification (Commentary) (protein specific)Renatured (Commentary) (protein specific)Source Tissue (protein specific)Specific Activity [micromol/min/mg] (protein specific)Storage Stability (protein specific)Substrates and Products (Substrate) (protein specific)Subunits (protein specific)Temperature Optimum [°C] (protein specific)Temperature Range [°C] (protein specific)Temperature Stability [°C] (protein specific)Turnover Number [1/s] (protein specific)pH Optimum (protein specific)pH Range (protein specific)pH Stability (protein specific)pI Value (protein specific)ExpressionGeneral InformationGeneral Information (protein specific)Expression (protein specific)KCat/KM [mM/s]KCat/KM [mM/s] (protein specific)
711325KataneThiolactomycin inhibits D-aspa ...Homo sapiens, Mus musculusBiochimie921371-13782010--1-1-6----2-4-----2--4-1---1--24-3--12-1-364----2-----2--4-1---1---------
711718KataneComparative characterization o ...Caenorhabditis elegansChem. Biodivers.71424-14342010--1----103--3-4--1-----411--91--1-----11------103--3---1----411--91----11-99
711719KataneD-aspartate oxidase: The sole ...Asterotremella humicola, Bos taurus, Caenorhabditis elegans, Homo sapiens, Mus musculus, Ovis aries, Rattus norvegicus, Sus scrofaChem. Biodivers.71435-14492010-25-4-24-12--17-8--5--40--288-------8----258-4--24--12--17---5-40--288---------44---
711721BurroneEffects of D-aspartate treatme ...Rana esculentaChem. Biodivers.71459-14662010--------1--1-3-----5--1--------1------1-------1--1-----5--1---------1221--
711722TopoThyroid hormones and D-asparti ...Mus musculus, Rattus norvegicusChem. Biodivers.71467-14782010-------2---2-6-----4--2--------2------2------2---2-----4--2----------22---
712616di GiovanniDistribution of free D-asparti ...Rana esculentaJ. Exp. Zool.313 A137-1432010-------10---3-2-----5--4-1---11---------------10---3-----5--4-1---11--1111--
712818YamamotoD-aspartate oxidase localisati ...Sus scrofaJ. Neuroendocrinol.221165-11722010--------1--1-4-----7--1-1---1--1------1-------1--1-----7--1-1---1---------
712787Takahashi-An active-site mutation enhanc ...Asterotremella humicolaJ. Mol. Catal. B61235-2402009--1-5--11---1-1--1---15-511--51--------1--5----11---1---1--15-511--51-------77
684387KataneHyperactive mutants of mouse D ...Mus musculusAmino Acids3575-822008--1-3--12-----3--1--112-2--------------1--3----12-------1-112-2---------------
686597HuangD-Aspartate and D-aspartate ox ...Mus musculusExp. Eye Res.86704-7092008-------------3-----2--1--------------------------------2--1---------------
673583KataneCaenorhabditis elegans has two ...Caenorhabditis elegansFEBS J.274137-1492007--1----10--4--4--1-----17----10---1-----11------10--4----1----17----10----------
684383KataneMolecular cloning of a cDNA en ...Mus musculusAmino Acids3269-782007--1-7-3---1--3-----2--7--------2-----12-7--3----1------2--7---------------
687440YamamotoFunctional and structural char ...Sus scrofaJ. Biochem.141363-37620072-1---23--2--4--1--22-31---31-11---2-11----2-3--2----1-22-31---31-1-------
677271TakahashiPhysiological role of D-aspart ...Asterotremella humicolaYeast221203-12122005-----------1-3--------1--------------------------1--------1---------------
655928TakahashiCloning and expression in Esch ...Asterotremella humicolaJ. Biochem.135533-5402004--1---23--1--7--1---1-311-231--------1-----2-3--1----1--1-311-231---------
657350Sarower-Distribution and substrate spe ...Marsupenaeus japonicus, Meretrix lusoria, Mizuhopecten yessoensis, Mytilus galloprovincialis, Octopus vulgaris, Procambarus clarkii, Todarodes pacificus, Turbo cornutusScience Asia30335-3402004-----------8-8-----14--16--------------------------8-----14--16---------------
656415SarowerDistribution and characteristi ...Chaunax fimbriatus, Cololabis saira, Cyprinus carpio, Dentex tumifrons, Lateolabrax japonicus, Oncorhynchus keta, Oncorhynchus masou, Oncorhynchus mykiss, Pagrus major, Paralichthys olivaceus, Plecoglossus altivelis, Pseudopleuronectes yokohamae, Sardinops melanostictus, Scomber japonicus, Thamnaconus tessellatus, Trachurus japonicus, Verasper variegatusJ. Exp. Zool. A295151-1592003------1117--17-21-----38--25-1---1--------------1-117--17-----38--25-1---1---------
391705SacchiEngineering the substrate spec ...Bos taurusJ. Biol. Chem.27727510-275162002------14---1-3-----1--5--------------------1-4---1-----1--5---------------
391706ZaarCellular and subcellular distr ...Bos taurus, Homo sapiens, Rattus norvegicusJ. Comp. Neurol.450272-282.2002--------3--3-6-----5--12--------3------3-------3--3-----5--12---------------
391707NegriPurification of beef kidney D- ...Bos taurusBiochim. Biophys. Acta1431212-2221999--1---110--21-4--1--31-111-------1-----11----1-10--21---1-31-111--------------
391708TedeschiD-Aspartate oxidase is present ...Bos taurus, Xenopus laevisComp. Biochem. Physiol. B124489-4941999------2---12-6--2--11--4--------2------2----2----12---2-11--4---------------
391709AmeryC-terminal tripeptide Ser-Asn- ...Homo sapiensBiochem. J.336367-3711998-11-----1--1-4--------2--------1----111-------1--1--------2---------------
391710Kera-D-Aspartate oxidase and free a ...Carassius auratus langsdorfii, Cyprinus carpio, Oncorhynchus mykiss, Pagrus major, Seriola quinqueradiataComp. Biochem. Physiol. B11995-1001998------7----9-5-----1111-24--------4------4----7-----9-----1111-24---------------
391711SimoniccDNA cloning and expression of ...Bos taurusBiochem. J.322729-7351997--1--------1-2-----2--2--------1-----11----------1-----2--2---------------
391712SetoyamaStructural and functional char ...Homo sapiensJ. Biochem.121798-8031997--1----2--11-3--1--2--4--------1-----11------2--11---1-2--4---------------
391713YamadaPurification and properties of ...Asterotremella humicolaBiochim. Biophys. Acta1294153-1581996------33--11-7--1---1-411---1--13-----1----333--11---1--1-411---1---------
391714TedeschiProperties of the flavoenzyme ...Octopus vulgarisBiochim. Biophys. Acta1207217-2221994-------6--11-6--------7------1-1------1------6--11--------7------1--------
391715Wakayama-Isolation, enzyme production a ...Fusarium sacchariJ. Ferment. Bioeng.78377-3791994-----------1-1--------4-1-1-1-11------1----------1--------4-1-1-1-1-------
391716D'AnielloBiological role of D-amino aci ...Mus musculus, Octopus vulgaris, Rattus norvegicusJ. Biol. Chem.26826941-269491993-----------3-5-----5--6--------3------3----------3-----5--6---------------
391717D'Aniello-Further study on the specifici ...Bos taurus, Octopus vulgarisComp. Biochem. Physiol. B105731-7341993-------14---2-2-----2--13--------2------2------14---2-----2--13---------------
391718TedeschiChemical modification of funct ...Bos taurusEur. J. Biochem.205127-1321992-----------1-3-----3--3--------1------1----------1-----3--3---------------
391719Negri-Structural studies of beef kid ...Bos taurusFlavins and Flavoproteins (Proc. Int. Symp., 10th, Meeting Date 1990, Curti, B., Ronchi S., Zanetti, G., eds.) de Gruyter, Berlin, New York179-1871990-------21-11-1--1--1--5----1---1------1------21-11---1-1--5----1----------
391720Tedeschi-Modification of substrate spec ...Bos taurusFlavins and Flavoproteins (Proc. Int. Symp., 10th, Meeting Date 1990, Curti, B., Ronchi S., Zanetti, G., eds.) de Gruyter, Berlin, New York189-1921990------1----1-1-----1--6--------1------1----1-----1-----1--6---------------
391721NegriThe kinetic mechanism of beef ...Bos taurusJ. Biol. Chem.26313557-135631988-------2---1-3-----2--21---2---1------1------2---1-----2--21---2----------
391722NegriD-Aspartate oxidase from beef ...Bos taurusJ. Biol. Chem.26210026-100341987----------11-3--1--31-2-------------------------11---1-31-2---------------
391723BurnsThiazolidine-2-carboxylate der ...Bos taurusBiochem. Biophys. Res. Commun.1251039-10451984-------4---1-3-----2--4----------------------4---1-----2--4---------------
391724NasuThe mammalian enzyme which rep ...Bos taurusBiochim. Biophys. Acta704240-2521982-----------1-4-----11-2--------1------1----------1-----11-2---------------
391725RinaldiOxidation of meso-diaminosucci ...Bos taurusEur. J. Biochem.117635-6381981-------2---2-3-----3--3--------1------1------2---2-----3--3---------------
391726JaroszewiczD-Asparatate oxidase in the th ...Sus scrofaEnzyme2080-891975------1-1--1-3--1--21-3-----1--1------1----1--1--1---1-21-3-----1---------
391727DixonD-aspartate oxidase of kidney ...Oryctolagus cuniculusBiochim. Biophys. Acta14654-761967------154---1-1--1--11-3-----211-2----------1524---1---1-11-3-----211-------
391728Still-On the prosthetic group of the ...Oryctolagus cuniculus, Ovis aries, Sus scrofaJ. Biol. Chem.182585-5891950------1----3-3-----2-16--------2------2----1-----3-----2-16---------------