EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.31 | resveratrol | increases the phosphorylation status of AMPK in wild-type MEFs. Effect of resveratrol on AMPK is mediated via LKB1 | Mus musculus | |
2.7.11.31 | resveratrol | resveratrol exerts anti-hypertrophic effects by activating AMPK via LKB1 and inhibiting Akt, thus suppressing protein synthesis and gene transcription. Level of phosphorylated AMPK is significantly increased in resveratrol-treated cardiac myocytes in the absence or presence of phenylephrine | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.31 | Mus musculus | - |
- |
- |
2.7.11.31 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.31 | cardiac myocyte | - |
Rattus norvegicus | - |
2.7.11.31 | MEF cell | mouse embryonic fibroblasts | Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.31 | ATP + acetyl-CoA carboxylase | - |
Mus musculus | ADP + [acetyl-CoA carboxylase]phosphate | - |
? | |
2.7.11.31 | ATP + acetyl-CoA carboxylase | - |
Rattus norvegicus | ADP + [acetyl-CoA carboxylase]phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.11.31 | AMP-activated protein kinase | - |
Mus musculus |
2.7.11.31 | AMP-activated protein kinase | - |
Rattus norvegicus |
2.7.11.31 | AMPK | - |
Mus musculus |
2.7.11.31 | AMPK | - |
Rattus norvegicus |