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BRENDA support

Literature summary for 6.5.1.1 extracted from

  • Paul, K.; Wang, M.; Mladenov, E.; Bencsik-Theilen, A.; Bednar, T.; Wu, W.; Arakawa, H.; Iliakis, G.
    DNA ligases I and III cooperate in alternative non-homologous end-joining in vertebrates (2013), PLoS ONE, 8, e59505.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.5.1.1

Organism

Organism UniProt Comment Textmining
Gallus gallus
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Source Tissue

Source Tissue Comment Organism Textmining
B-cell chicken B-cell system DT40 is used Gallus gallus
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Synonyms

Synonyms Comment Organism
DNA ligase I
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 Gallus gallus
DNA ligase III
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 Gallus gallus
LIG1
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 Gallus gallus
Lig3
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 Gallus gallus

General Information

General Information Comment Organism
physiological function using chicken B-cell system DT40 and conditioned knockout strategies it is shown that LIG1 and LIG3 are able to support double-strand break (DSB) repair by backup non-homologous end joining (B-NHEJ) with similar activity in interchangeable manner Gallus gallus