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Literature summary for 6.5.1.1 extracted from

  • Arakawa, H.; Bednar, T.; Wang, M.; Paul, K.; Mladenov, E.; Bencsik-Theilen, A.A.; Iliakis, G.
    Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells (2012), Nucleic Acids Res., 40, 2599-2610.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.5.1.1

Organism

Organism UniProt Comment Textmining
Gallus gallus
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Source Tissue

Source Tissue Comment Organism Textmining
B-lymphocyte cell line chicken B-cell line DT40 is used Gallus gallus
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Synonyms

Synonyms Comment Organism
DNA ligase III
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 Gallus gallus
LIG1
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 Gallus gallus
Lig3
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 Gallus gallus
LigI
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 Gallus gallus
LigIII
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 Gallus gallus

General Information

General Information Comment Organism
malfunction using chicken B-cell line DT40 and a conditional knockout strategy is shown that LIG3, but not LIG1 or LIG4, is essential for DT40 survival Gallus gallus
physiological function LigIII functions as the primary ligase in DNA replication in the absence of LigI. A functional redundancy between LigI and LigIII in DNA replication is indicated Gallus gallus