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Literature summary for 6.5.1.1 extracted from
- Involvement of DNA ligase III and ribonuclease H1 in mitochondrial DNA replication in cultured human cells (2011), Biochim. Biophys. Acta, 1813, 2000-2007.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| 143B cell | studies carried out in thymidine kinase 1-deficient human osteosarcoma cell line (143B [TK-]) | Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DNA ligase III | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | DNA ligase III knockdown attenuates the recovery of mtDNA copy number and causes single strand nicks in replicating mtDNA molecules, suggesting the involvement of DNA ligase III in Okazaki fragment ligation in human mitochondria | Homo sapiens |
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