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Literature summary for 6.5.1.1 extracted from

  • Riballo, E.; Woodbine, L.; Stiff, T.; Walker, S.A.; Goodarzi, A.A.; Jeggo, P.A.
    XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation (2008), Nucleic Acids Res., 37, 482-492.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.5.1.1

Activating Compound

Activating Compound Comment Organism Structure
XLF-Cernunnos a component of the DNA ligase IV-XRCC4 complex, which functions during DNA non-homologous end joining and stimulates ligase IV re-adenylation following ligation Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
2BN cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Homo sapiens AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?

Synonyms

Synonyms Comment Organism
DNA ligase IV
-
 Homo sapiens
DNA ligase IV-XRCC4 complex
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens