Literature summary for 6.5.1.1 extracted from

Pascal, J.M.
DNA and RNA ligases: structural variations and shared mechanisms (2008), Curr. Opin. Struct. Biol., 18, 96-105.

Search for more literature for 6.5.1.1

Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with the AMP-DNA reaction intermediate	Homo sapiens
in complex with the AMP-DNA reaction intermediate	Pyrococcus furiosus
in complex with the AMP-DNA reaction intermediate	Saccharolobus solfataricus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Pyrococcus furiosus	-	-	-
Saccharolobus solfataricus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m	-	Homo sapiens	AMP + diphosphate + (deoxyribonucleotide)m+n	-	?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m	-	Pyrococcus furiosus	AMP + diphosphate + (deoxyribonucleotide)m+n	-	?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m	-	Saccharolobus solfataricus	AMP + diphosphate + (deoxyribonucleotide)m+n	-	?

Synonyms

Synonyms	Comment	Organism
DNA ligase	-	Pyrococcus furiosus
DNA ligase	-	Saccharolobus solfataricus
DNA ligase I	-	Homo sapiens
LIG1	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens
ATP	-	Pyrococcus furiosus
ATP	-	Saccharolobus solfataricus

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Release 2023.1 (January 2023)