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Literature summary for 6.5.1.1 extracted from

  • Karimi-Busheri, F.; Lee, J.; Tomikson, A.E.; Weinfeld, M.
    Repair of DNA strand gaps and nicks containing 3'-phosphate and 5'-hydroxyl termini by purified mammalian enzymes (1998), Nucleic Acids Res., 26, 4395-4400.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m Homo sapiens
-
AMP + diphosphate + (deoxyribonucleotide)m+n
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant DNA ligase I Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
Homo sapiens AMP + diphosphate + (deoxyribonucleotide)m+n
-
?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m the concerted reaction of polynucleotide kinase and DNA ligase I can efficiently repair DNA nicks possessing 3'-phosphate and 5'-hydroxyl termini Homo sapiens AMP + diphosphate + (deoxyribonucleotide)m+n
-
?

Synonyms

Synonyms Comment Organism
DNA ligase I
-
Homo sapiens