Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Anthracycline derivatives | inhibit human DNA ligase I and rat DNA ligase I and III in the poly[d(A-T)] joining assay | Homo sapiens | |
Anthracycline derivatives | inhibit human DNA ligase I and rat DNA ligase I and III in the poly[d(A-T)] joining assay | Rattus norvegicus | |
Distamycin | and derivatives, inhibit human DNA ligase I and rat DNA ligase I and III in the poly[d(A-T)] joining assay | Homo sapiens | |
Distamycin | and derivatives, inhibit human DNA ligase I and rat DNA ligase I and III in the poly[d(A-T)] joining assay | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
DNA ligase I | - |
Rattus norvegicus | - |
DNA ligase I and III | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | - |
Homo sapiens | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | - |
Rattus norvegicus | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? |