Cloned (Comment) | Organism |
---|---|
gene carB, DNA and amino acid sequence determination and analysis | Streptococcus thermophilus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction by gene replacement and phenotype of a carbamoylphosphate synthetase-negative mutant A17, i.e. DELTAcarB, overview. CO2 depletion or carB gene inactivation determines the auxotrophy of Streptococcus thermophilus for L-arginine and uracil. The parent strain grows faster than the mutant, even when milk is supplemented with uracil or arginine | Streptococcus thermophilus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + L-glutamine + HCO3- + H2O | Streptococcus thermophilus | - |
2 ADP + phosphate + L-glutamate + carbamoyl phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus thermophilus | B2G3Q3 | carB; DSM20617, gene carB | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | growth medium is bovine milk | Streptococcus thermophilus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + L-glutamine + HCO3- + H2O | - |
Streptococcus thermophilus | 2 ADP + phosphate + L-glutamate + carbamoyl phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CPS | - |
Streptococcus thermophilus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Streptococcus thermophilus |
General Information | Comment | Organism |
---|---|---|
physiological function | carbamoylphosphate synthetase activity is essential for the optimal growth and acidification of Streptococcus thermophilus in cow milk | Streptococcus thermophilus |