Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme from fetal liver extracts is significantly inhibited when combined with adult liver or tumor extracts | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.31 | - |
L-Asp | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | divalent metal ion required, Mg2+ more effective than Mn2+ | Rattus norvegicus | |
Mn2+ | 10% of the activity relative to Mg2+ | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | low | Rattus norvegicus | - |
breast cancer cell line | carcinoma | Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | high activity in fetal liver and low activity in adult liver | Rattus norvegicus | - |
LLC-WRC 256 cell | - |
Rattus norvegicus | - |
lung | - |
Rattus norvegicus | - |
McA-RH7777 cell | - |
Rattus norvegicus | - |
ovary | - |
Rattus norvegicus | - |
pancreas | adult pancreas is the most active tissue found | Rattus norvegicus | - |
small intestine | low | Rattus norvegicus | - |
spleen | low | Rattus norvegicus | - |
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-Asp + L-Gln | - |
Rattus norvegicus | AMP + diphosphate + Asn + Glu | - |
? | |
ATP + L-Asp + NH3 | 85% of the activity relative to Gln | Rattus norvegicus | AMP + diphosphate + Asn | - |
? | |
additional information | ATP-diphosphate exchange reaction | Rattus norvegicus | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 8 | - |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 8.5 | minor variation of activity in this pH range | Rattus norvegicus |