Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | weak | Rattus norvegicus | |
AMP | weak | Rattus norvegicus | |
Asn | - |
Rattus norvegicus | |
Carbamoyl phosphate | - |
Rattus norvegicus | |
CMP | weak | Rattus norvegicus | |
CTP | - |
Rattus norvegicus | |
diphosphate | - |
Rattus norvegicus | |
GDP | weak | Rattus norvegicus | |
GMP | weak | Rattus norvegicus | |
GTP | - |
Rattus norvegicus | |
IMP | weak | Rattus norvegicus | |
iodoacetamide | - |
Rattus norvegicus | |
ITP | - |
Rattus norvegicus | |
NEM | - |
Rattus norvegicus | |
nucleoside triphosphates | except ATP | Rattus norvegicus | |
p-chloromercuribenzoate | - |
Rattus norvegicus | |
sulfhydryl reagents | - |
Rattus norvegicus | |
UMP | weak | Rattus norvegicus | |
UTP | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.14 | - |
ATP | - |
Rattus norvegicus | |
0.76 | - |
L-Asp | - |
Rattus norvegicus | |
4.3 | - |
L-Gln | - |
Rattus norvegicus | |
10 | - |
NH4+ | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cl- | required, Km: 1.7 mM | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
110000 | - |
gel filtration | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-Asp + L-Gln | - |
Rattus norvegicus | AMP + diphosphate + Asn + Glu | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
additional information | - |
a combination of L-Asp, ATP, and Mg2+ protects against heat inactivation | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | 7.6 | Gln-dependent activity | Rattus norvegicus |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
8 | - |
most stable around pH 8 at 4°C | Rattus norvegicus |