Literature summary for 6.3.4.4 extracted from

Schmitzer, P.R.; Graupner, P.R.; Chapin, E.L.; Fields, S.C.; Gilbert, J.R.; Gray, J.A.; Peacock, C.L.; Gerwick, B.C.
Ribofuranosyl triazolone: A natural product herbicide with activity on adenylosuccinate synthetase following phosphorylation (2000), J. Nat. Prod., 63, 777-781.

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Inhibitors

Inhibitors	Comment	Organism	Structure
2,4-dihydro-4-(beta-D-ribofuranosyl)-1,2,4(3H)-triazol-3-one	-	Abutilon theophrasti
2,4-dihydro-4-(beta-D-ribofuranosyl)-1,2,4(3H)-triazol-3-one	-	Alopecurus myosuroides
2,4-dihydro-4-(beta-D-ribofuranosyl)-1,2,4(3H)-triazol-3-one	-	Amaranthus retroflexus
2,4-dihydro-4-(beta-D-ribofuranosyl)-1,2,4(3H)-triazol-3-one	-	Arabidopsis thaliana
2,4-dihydro-4-(beta-D-ribofuranosyl)-1,2,4(3H)-triazol-3-one	-	Avena fatua
2,4-dihydro-4-(beta-D-ribofuranosyl)-1,2,4(3H)-triazol-3-one	-	Echinochloa crus-galli
2,4-dihydro-4-(beta-D-ribofuranosyl)-1,2,4(3H)-triazol-3-one	-	Helianthus annuus
2,4-dihydro-4-(beta-D-ribofuranosyl)-1,2,4(3H)-triazol-3-one	-	Ipomoea hederacea
2,4-dihydro-4-(beta-D-ribofuranosyl)-1,2,4(3H)-triazol-3-one	-	Setaria faberi

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
GTP + IMP + L-aspartate	Arabidopsis thaliana	-	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	Helianthus annuus	-	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	Echinochloa crus-galli	-	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	Amaranthus retroflexus	-	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	Avena fatua	-	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	Setaria faberi	-	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	Alopecurus myosuroides	-	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	Ipomoea hederacea	-	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	Abutilon theophrasti	-	GDP + phosphate + adenylosuccinate	-	?

Organism

Organism	UniProt	Comment	Textmining
Abutilon theophrasti	-	-	-
Alopecurus myosuroides	-	-	-
Amaranthus retroflexus	-	-	-
Arabidopsis thaliana	-	-	-
Avena fatua	-	-	-
Echinochloa crus-galli	-	-	-
Helianthus annuus	-	-	-
Ipomoea hederacea	-	-	-
Setaria faberi	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GTP + IMP + L-aspartate	-	Arabidopsis thaliana	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	-	Helianthus annuus	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	-	Echinochloa crus-galli	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	-	Amaranthus retroflexus	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	-	Avena fatua	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	-	Setaria faberi	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	-	Alopecurus myosuroides	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	-	Ipomoea hederacea	GDP + phosphate + adenylosuccinate	-	?
GTP + IMP + L-aspartate	-	Abutilon theophrasti	GDP + phosphate + adenylosuccinate	-	?

Synonyms

Synonyms	Comment	Organism
Adenylosuccinate synthetase	-	Arabidopsis thaliana
Adenylosuccinate synthetase	-	Helianthus annuus
Adenylosuccinate synthetase	-	Echinochloa crus-galli
Adenylosuccinate synthetase	-	Amaranthus retroflexus
Adenylosuccinate synthetase	-	Avena fatua
Adenylosuccinate synthetase	-	Setaria faberi
Adenylosuccinate synthetase	-	Alopecurus myosuroides
Adenylosuccinate synthetase	-	Ipomoea hederacea
Adenylosuccinate synthetase	-	Abutilon theophrasti

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Release 2023.1 (January 2023)