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Literature summary for 6.3.4.4 extracted from

  • Prade, L.; Cowan-Jacob, S.W.; Chemla, P.; Potter, S.; Ward, E.; Fonne-Pfister, R.
    Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana (2000), J. Mol. Biol., 296, 569-577.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
cDNA expressed in Escherichia coli Triticum aestivum
cDNA expressed in Escherichia coli Arabidopsis thaliana

Crystallization (Commentary)

Crystallization (Comment) Organism
space group I23, cell constants a = b = c = 212.76 A Arabidopsis thaliana
space group P4(1)2(1)2, cell constants a = b = 151.44 A, c = 91.94A Triticum aestivum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
2 * 55000 Triticum aestivum
55000
-
2 * 55000 Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + IMP + L-aspartate Arabidopsis thaliana catalyzing the first step in the de novo synthesis of adenylmonophosphate GDP + phosphate + adenylosuccinate
-
?
GTP + IMP + L-aspartate Triticum aestivum catalyzing the first step in the de novo sythesis of adenylmonophosphate GDP + phosphate + adenylosuccinate
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q96529
-
-
Triticum aestivum O24396 wheat
-

Purification (Commentary)

Purification (Comment) Organism
-
Triticum aestivum
-
Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + IMP + L-aspartate
-
Triticum aestivum GDP + phosphate + adenylosuccinate
-
?
GTP + IMP + L-aspartate
-
Arabidopsis thaliana GDP + phosphate + adenylosuccinate
-
?
GTP + IMP + L-aspartate catalyzing the first step in the de novo synthesis of adenylmonophosphate Arabidopsis thaliana GDP + phosphate + adenylosuccinate
-
?
GTP + IMP + L-aspartate catalyzing the first step in the de novo sythesis of adenylmonophosphate Triticum aestivum GDP + phosphate + adenylosuccinate
-
?

Subunits

Subunits Comment Organism
homodimer 2 * 55000 Triticum aestivum
homodimer 2 * 55000 Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
Adenylosuccinate synthetase
-
Triticum aestivum
Adenylosuccinate synthetase
-
Arabidopsis thaliana
AdSS
-
Triticum aestivum
AdSS
-
Arabidopsis thaliana
Arabdss
-
Arabidopsis thaliana
Wheatadss
-
Triticum aestivum