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Literature summary for 6.3.2.9 extracted from

  • Good, C.M.; Tipper, D.J.
    Conditional mutants of Staphylococcus aureus defective in cell wall precursor synthesis (1972), J. Bacteriol., 111, 231-241.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
TOF-123 mutant enzyme TOF-95 is almost indistinguishable from wild type, glutamate-adding activity of mutant enzyme TOF-9 is about 17% of wild-type at 30 C and less at 43 C, no glutamate-adding activity can be detected in TOF-123 mutant enzyme, activity of mutant enzyme TOF-1 is marginally reduced to about 85% of wild type Staphylococcus aureus
TOF-9 mutant enzyme TOF-95 is almost indistinguishable from wild type, glutamate-adding activity of mutant enzyme TOF-9 is about 17% of wild-type at 30 C and less at 43 C, no glutamate-adding activity can be detected in TOF-123 mutant enzyme, activity of mutant enzyme TOF-1 is marginally reduced to about 85% of wild type Staphylococcus aureus
TOF-95 mutant enzyme TOF-95 is almost indistinguishable from wild type, glutamate-adding activity of mutant enzyme TOF-9 is about 17% of wild-type at 30 C and less at 43 C, no glutamate-adding activity can be detected in TOF-123 mutant enzyme, activity of mutant enzyme TOF-1 is marginally reduced to about 85% of wild type Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
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temperature-sensitive mutants with defective cell wall biosynthesis, TOF-95, TOF-9, TOF-123, TOF-1
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + UDP-N-acetylmuramoyl-L-Ala + Glu
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Staphylococcus aureus ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-Glu
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