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Literature summary for 6.3.2.17 extracted from

  • Wettergren, Y.; Odin, E.; Nilsson, S.; Carlsson, G.; Gustavsson, B.
    p161NK4a gene promoter hypermethylation in mucosa as a prognostic factor for patients with colorectal cancer (2008), Mol. Med., 14, 412-421.
No PubMed abstract available

Application

Application Comment Organism
medicine reduced folate carrier-1 and folylpolyglutamate synthase gene expression levels are significantly correlated in patients lacking p16 promoter hypermethylation in mucosa, but not at all correlated in patients having hypermethylation in mucosa. p16 Hypermethylation in mucosa of colorectal cancer patients is an independent prognostic parameter for cancer-specific survival as well as an independent predictor of disease-free survival Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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patients with colorectal cancer
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