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Literature summary for 6.3.2.1 extracted from

  • Wang, S.; Eisenberg, D.
    Crystal structure of the pantothenate synthetase from Mycobacterium tuberculosis, snapshots of the enzyme in action (2006), Biochemistry, 45, 1554-1561.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure of the enzyme complexed with AMP, ATP or beta-alanine Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis P9WIL5
-
-
Mycobacterium tuberculosis H37Rv P9WIL5
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (R)-pantoate + beta-alanine the phosphate group of AMP serves as an anchor for the binding of beta-alanine Mycobacterium tuberculosis AMP + diphosphate + (R)-pantothenate
-
?
ATP + (R)-pantoate + beta-alanine the phosphate group of AMP serves as an anchor for the binding of beta-alanine Mycobacterium tuberculosis H37Rv AMP + diphosphate + (R)-pantothenate
-
?