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Literature summary for 6.3.1.2 extracted from

  • Galmozzi, C.V.; Saelices, L.; Florencio, F.J.; Muro-Pastor, M.I.
    Posttranscriptional regulation of glutamine synthetase in the filamentous cyanobacterium Anabaena sp. PCC 7120: differential expression between vegetative cells and heterocysts (2010), J. Bacteriol., 192, 4701-4711.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
additional information presence of only one glutathione synthetase inactivation factor, 7A, encoded by open reading frame asl2329, gifA, in strain PCC 7120. Upon addition of ammonium, expression of gifA is derepressed, leading to the synthesis of IF7A, and consequently, glutathione synthetase is inactivated. Upon ammonium removal, the glutathione synthetase activity returns to the initial level and IF7A becomes undetectable. Anabaena glutathione synthetase is not inactivated by Synechocystis IFs. In an Anabaena strain expressing a second inactivating factor, containing the amino-terminal part of IF17 from Synechocystis fused to IF7A, glutathione synthetase inactivation is more effective than that in the wild-ype and resembles that observed in Synechocystis Anabaena sp.

Organism

Organism UniProt Comment Textmining
Anabaena sp.
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-
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Anabaena sp. PCC 7120
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-
-

Source Tissue

Source Tissue Comment Organism Textmining

General Information

General Information Comment Organism
metabolism presence of only one glutathione synthetase inactivation factor, 7A, encoded by open reading frame asl2329, gifA. Following addition of ammonium, expression of gifA is derepressed, leading to the synthesis of IF7A, and consequently, glutathione synthetase is inactivated. Upon ammonium removal, the glutathione synthetase activity returns to the initial level and IF7A becomes undetectable. Anabaena glutathione synthetase is not inactivated by Synechocystis IFs. In an Anabaena strain expressing a second inactivating factor, containing the amino-terminal part of IF17 from Synechocystis fused to IF7A, glutathione synthetase inactivation is more effective than that in the wild-ype and resembles that observed in Synechocystis Anabaena sp.