Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | CODH/ACS uses a Ni-Fe-S center called the C-cluster to reduce carbon dioxide to carbon monoxide and uses a second Ni-Fe-S center, called the A-cluster, to assemble acetyl-CoA from a methyl group, coenzyme A, and C-cluster-generated CO | Moorella thermoacetica | |
additional information | the enzyme uses seven metalloclusters in four reaction steps, overview | Moorella thermoacetica |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
310000 | - |
- |
Moorella thermoacetica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Moorella thermoacetica | CODH/ACS is a bifunctional enzyme that is responsible for the reduction of CO2 to CO and subsequent assembly of acetyl-CoA, as part of the Wood-Ljungdahl carbon fixation pathway, the enzyme is a key player in the global carbon cycle | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Moorella thermoacetica | - |
formerly Clostridium thermoaceticum strain ATCC 39073 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | CODH/ACS is a bifunctional enzyme that is responsible for the reduction of CO2 to CO and subsequent assembly of acetyl-CoA, as part of the Wood-Ljungdahl carbon fixation pathway, the enzyme is a key player in the global carbon cycle | Moorella thermoacetica | ? | - |
? | |
additional information | the enzyme is a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase, Moorella thermoacetica CODH/ACS contains a very long enzyme channel to allow for intermolecular CO transport, mechanism and reaction steps, overview. Structure-function analysis in comparison to monofunctional Acs, overview | Moorella thermoacetica | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | Moorella thermoacetica CODH/ACS contains a very long enzyme channel to allow for intermolecular CO transport, overview | Moorella thermoacetica |
tetramer | alpha2beta2 | Moorella thermoacetica |
Synonyms | Comment | Organism |
---|---|---|
carbon monoxide dehydrogenase/acetyl-CoA synthase | - |
Moorella thermoacetica |
mtCODH/ACS | - |
Moorella thermoacetica |