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Literature summary for 6.1.1.1 extracted from

  • Park, H.; Davidson, E.; King, M.P.
    Overexpressed mitochondrial leucyl-tRNA synthetase suppresses the A3243G mutation in the mitochondrial tRNA(Leu(UUR)) gene (2008), RNA, 14, 2407-2416.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
biotechnology a mutant Methanococcus jannaschii tyrosyl amber suppressor tRNA, Tyr MjtRNA CUR/tyrosyl-tRNA synthetase (MjTyrRS) pair is developed to uniquely incorporate phenylselenocysteine in response to the amber TAG codon in Escherichia coli. After being efficiently converted into dehydroalanine under mild conditions, Michael addition reactions with the corresponding thiols can be used to synthesize N-methyl- and N-acetyl-lysine analogues Methanocaldococcus jannaschii

Organism

Organism UniProt Comment Textmining
Methanocaldococcus jannaschii
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Synonyms

Synonyms Comment Organism
tyrosyl—tRNA synthetase
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Methanocaldococcus jannaschii