Literature summary for 5.5.1.6 extracted from

Qin, J.C.; Zhu, L.; Gao, M.J.; Wu, X.; Pan, H.Y.; Zhang, Y.S.; Li, X.
Cloning and functional characterization of a chalcone isomerase from Trigonella foenum-graecum L (2011), Planta Med., 77, 765-770.

Search for more literature for 5.5.1.6

Cloned(Commentary)

Cloned (Comment)	Organism
gene TFGCHI-1, cloning from leaves, DNA and amino acid sequence determination and analysis, phylogenetic tree, quantitative real-time PCR expression analysis, recombinant expression in Escherichia coli strains DH10B and BL21(DE3), functional complementation of CHI-deficient Arabidopsis thaliana loss-of-function mutant tt5	Trigonella foenum-graecum

Organism

Organism	UniProt	Comment	Textmining
Trigonella foenum-graecum	-	gene TFGCHI-1	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leaf	-	Trigonella foenum-graecum	-
seed	-	Trigonella foenum-graecum	-
stem	-	Trigonella foenum-graecum	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
naringenin chalcone	i.e. 6'-hydroxychalcone	Trigonella foenum-graecum	naringenin	-	?

Synonyms

Synonyms	Comment	Organism
Chi-1	-	Trigonella foenum-graecum

General Information

General Information	Comment	Organism
metabolism	CHI catalyzes the first step in flavonoid biosynthesis pathway, overview	Trigonella foenum-graecum
physiological function	CHI converts chalcones into the corresponding flavanones by selectively binding an ionized chalcone in a conformation conducive to ring closure in a diffusion controlled reaction, thus accelerating the stereochemically defined intramolecular cyclization reaction yielding a biologically active (S)-isomer	Trigonella foenum-graecum

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Release 2023.1 (January 2023)