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Literature summary for 5.4.99.7 extracted from

  • Duniec-Dmuchowski, Z.; Fang, H.L.; Strom, S.C.; Ellis, E.; Runge-Morris, M.; Kocarek, T.A.
    Human pregnane X receptor activation and CYP3A4/CYP2B6 induction by 2,3-oxidosqualene:lanosterol cyclase inhibition (2009), Drug Metab. Dispos., 37, 900-908.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.4.99.7

Inhibitors

Inhibitors Comment Organism Structure
3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride U18666A Homo sapiens
4-chloro-N-(4-{4-[(dimethylamino)methyl]phenyl}cyclohexyl)-N-methylbenzamide BIBX 79 Homo sapiens
[4'-(6-allyl-methyl-amino-hexyloxy)-2'-fluoro-phenyl]-(4-bromophenyl)-methanone fumarate Ro 48-8071 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
 Homo sapiens
-
hepatocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-squalene-2,3-epoxide
-
 Homo sapiens Lanosterol
-
 ?

Synonyms

Synonyms Comment Organism
2,3-oxidosqualene:lanosterol cyclase
-
 Homo sapiens
OSC
-
 Homo sapiens