Literature summary for 5.4.99.7 extracted from

Wu, T.K.; Wen, H.Y.; Chang, C.H.; Liu, Y.T.
Protein plasticity: a single amino acid substitution in the Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase generates protosta-13(17),24-dien-3beta-ol, a rearrangement product (2008), Org. Lett., 10, 2529-2532.

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Protein Variants

Protein Variants	Comment	Organism
F699C	inactive	Saccharomyces cerevisiae
F699Q	inactive	Saccharomyces cerevisiae
F699S	inactive	Saccharomyces cerevisiae
F699T	the mutant produces protosta-13(17),24-dien-3beta-ol from (S)-2,3-oxidosqualene	Saccharomyces cerevisiae
F699Y	inactive	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(S)-2,3-oxidosqualene	-	Saccharomyces cerevisiae	lanosterol	-	?

Synonyms

Synonyms	Comment	Organism
ERG7	-	Saccharomyces cerevisiae
OSC	-	Saccharomyces cerevisiae
Oxidosqualene-lanosterol cyclase	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)