Literature summary for 5.4.99.7 extracted from

Cattel, L.; Ceruti, M.; Balliano, G.; Viola, F.; Grosa, G.; Rocco, F.; Brusa, P.
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors (1995), Lipids, 30, 235-246.

Search for more literature for 5.4.99.7

Inhibitors

Inhibitors	Comment	Organism	Structure
(6E)-10-Aza-10,11-dihydrosqualene-2,3-epoxide	-	Candida albicans
(6E)-10-Aza-10,11-dihydrosqualene-2,3-epoxide	-	Rattus norvegicus
(6E)-10-Aza-10,11-dihydrosqualene-2,3-epoxide	-	Saccharomyces cerevisiae
(6E)-10-Aza-10,11-dihydrosqualene-2,3-epoxide	-	Sus scrofa
19-Azasqualene	-	Candida albicans
19-Azasqualene	-	Rattus norvegicus
19-Azasqualene	-	Saccharomyces cerevisiae
19-Azasqualene	-	Sus scrofa
19-Azasqualene-2,3-epoxide	-	Candida albicans
19-Azasqualene-2,3-epoxide	-	Rattus norvegicus
19-Azasqualene-2,3-epoxide	-	Saccharomyces cerevisiae
19-Azasqualene-2,3-epoxide	-	Sus scrofa
2-Aza-2,3-dihydrosqualene	-	Rattus norvegicus
2-aza-2,3-dihydrosqualene alcohol	-	Rattus norvegicus
2-Aza-2,3-dihydrosqualene N-oxide	-	Rattus norvegicus
22,23-Epoxy-2-aza-2,3-dihydrosqualene	slight	Rattus norvegicus
Squalene maleimide	-	Rattus norvegicus
Squalene maleimide	-	Sus scrofa

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
microsome	-	Rattus norvegicus	-	-
microsome	-	Sus scrofa	-	-
microsome	-	Saccharomyces cerevisiae	-	-
microsome	-	Candida albicans	-	-

Organism

Organism	UniProt	Comment	Textmining
Candida albicans	-	-	-
Rattus norvegicus	-	-	-
Saccharomyces cerevisiae	-	-	-
Sus scrofa	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-
liver	-	Sus scrofa	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(S)-squalene-2,3-epoxide	-	Rattus norvegicus	Lanosterol	-	?
(S)-squalene-2,3-epoxide	-	Sus scrofa	Lanosterol	-	?
(S)-squalene-2,3-epoxide	-	Saccharomyces cerevisiae	Lanosterol	-	?
(S)-squalene-2,3-epoxide	-	Candida albicans	Lanosterol	-	?

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Release 2023.1 (January 2023)