Literature summary for 5.4.99.17 extracted from

Englund, E.; Pattanaik, B.; Ubhayasekera, S.J.; Stensjoe, K.; Bergquist, J.; Lindberg, P.
Production of squalene in Synechocystis sp. PCC 6803 (2014), PLoS ONE, 9, e90270.

Search for more literature for 5.4.99.17

Application

Application	Comment	Organism
synthesis	it is possible to use the cyanobacterium Synechocystis to generate squalene, a hydrocarbon of commercial interest and a potential biofuel	Synechocystis sp.

Cloned(Commentary)

Cloned (Comment)	Organism
gene slr2089, DNA and amino acid sequence determination and analysis, sequence comparison, expression in Escherichia coli strain DH5alpha	Synechocystis sp.

Protein Variants

Protein Variants	Comment	Organism
additional information	knockout of gene slr2089, phenotype and self-complementation by gene slr2089 expression	Synechocystis sp.

Organism

Organism	UniProt	Comment	Textmining
Synechocystis sp.	P73914	gene slr2089	-

Synonyms

Synonyms	Comment	Organism
SHC	-	Synechocystis sp.
squalene hopene cyclase	-	Synechocystis sp.

General Information

General Information	Comment	Organism
malfunction	inactivation of slr2089 leads to accumulation of squalene to a level over 70times higher than in wild-type cells, but no significant growth deficiency in the DELTAshc strain occur compared to the wild-type Synechocystis even at high light conditions	Synechocystis sp.
metabolism	the enzyme converts squalene into hopene, the substrate for forming hopanoids	Synechocystis sp.

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Release 2023.1 (January 2023)