Any feedback?
Literature summary for 5.4.99.17 extracted from
- Squalene-hopene cyclase: catalytic mechanism and substrate recognition (2002), Chem. Commun. (Camb.), 2000, 291-301.
No PubMed abstract available
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Alicyclobacillus acidocaldarius |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | overview | Alicyclobacillus acidocaldarius |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | sulfur-substituted oxidosqualene analogues serve as inhibitors | Alicyclobacillus acidocaldarius | |
| N,N-dimethyldodecylamine N-oxide | forms a complex with the enzyme | Alicyclobacillus acidocaldarius |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | Km for wild type and mutant enzymes | Alicyclobacillus acidocaldarius |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Alicyclobacillus acidocaldarius | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
specific activities for wild type and mutant enzymes | Alicyclobacillus acidocaldarius |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | overview of cyclization products of wild type and mutant enzymes | Alicyclobacillus acidocaldarius | ? | - |
? | |
| squalene | - |
Alicyclobacillus acidocaldarius | hop-22(29)-ene | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| additional information | - |
wild type and mutant enzymes | Alicyclobacillus acidocaldarius |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | wild type and mutant enzymes | Alicyclobacillus acidocaldarius |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | Ki for sulfur-substituted oxidosqualene analogues | Alicyclobacillus acidocaldarius |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
