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Literature summary for 5.4.99.12 extracted from

  • Chen, J.; Patton, J.R.
    Pseudouridine synthase 3 from mouse modifies the anticodon loop of tRNA (2000), Biochemistry, 39, 12723-12730.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55552
-
x * 55552, calculated Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
tRNA uridine39 Mus musculus with tRNA substrates from both yeast and humans, uridines at position 39 are modified to pseudouridine. In a tRNA substrate with a uridine at position 38 (human tRNALeu), there is very slight formation of pseudouridine at that position after incubation with mPus3p tRNA pseudouridine39
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus Q9JI38
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
human tRNALeu uridine 38 uridine39
-
Mus musculus human tRNALeu pseudouridine 38 pseudouridine39 psuedouridine formation in position 39 is clearly preferred over position 38 ?
human tRNALys3
-
Mus musculus ?
-
?
human tRNASer uridine39
-
Mus musculus human tRNASer pseudouridine39
-
?
tRNA uridine39 with tRNA substrates from both yeast and humans, uridines at position 39 are modified to pseudouridine. In a tRNA substrate with a uridine at position 38 (human tRNALeu), there is very slight formation of pseudouridine at that position after incubation with mPus3p Mus musculus tRNA pseudouridine39
-
?
yeast tRNAPhe
-
Mus musculus ?
-
?

Subunits

Subunits Comment Organism
? x * 55552, calculated Mus musculus

Synonyms

Synonyms Comment Organism
mPus3p
-
Mus musculus
pseudouridine synthase 3
-
Mus musculus