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Literature summary for 5.3.99.3 extracted from

  • Wu, D.; Mennerich, D.; Arndt, K.; Sugiyama, K.; Ozaki, N.; Schwarz, K.; Wei, J.; Wu, H.; Bishopric, N.H.; Doods, H.
    The effects of microsomal prostaglandin E synthase-1 deletion in acute cardiac ischemia in mice (2009), Prostaglandins Leukot. Essent. Fatty Acids, 81, 31-33.
    View publication on PubMed
Search for more literature for 5.3.99.3

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Mus musculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Prostaglandin H2 Mus musculus
-
 Prostaglandin E2
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2
-
 Mus musculus Prostaglandin E2
-
 ?

Synonyms

Synonyms Comment Organism
microsomal prostaglandin E synthase-1
-
 Mus musculus
mPGES-1
-
 Mus musculus

General Information

General Information Comment Organism
malfunction the deletion of mPGES-1 in mice results in increased prostacyclin I2 formation and marginal effects on the circulatory prostaglandin E2 level. Loss of mPGES-1 results in increased prostacyclin I2 formation, and in contrast to inhibition of prostacyclin I2, without worsening acute cardiac ischemic injury Mus musculus