Protein Variants | Comment | Organism |
---|---|---|
additional information | in mice with targeted disruption of isoform mPGES-1 gene, basal excretion of prostaglandin E2 in urine is decreased by 50%. In female enzyme-deficient mice, there is a reciprocal increase in basal excretion of other prostanoids. Urinary osmolalities are similar in wild-type and enzyme deficient animals at baseline and after 12 h of water deprivation, and there are no differences in blood pressure on control or high- or low-salt diet. Furesemide-associated diuresis is reduced in male enzyme-deficient animals | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Mus musculus | - |