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Literature summary for 5.3.99.3 extracted from

  • Mehrotra, S.; Morimiya, A.; Agarwal, B.; Konger, R.; Badve, S.
    Microsomal prostaglandin E(2) synthase-1 in breast cancer: a potential target for therapy (2006), J. Pathol., 208, 356-363.
    View publication on PubMed

Application

Application Comment Organism
drug development the enzyme is a potential target for therapy of breast cancer Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast in normal breast the enzyme is seen in myoepithelial cells and in stromal fibroblasts and vascular smooth muscle, in breast disease, the enzyme is observed in epithelial cells adjacent to cancer, in scattered foci of fibrocystic disease, in ductal carcinoma in situ and in invasive cancers, in addition to myoepithelial cells Homo sapiens
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MCF-10A cell
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Homo sapiens
-
MCF-7 cell
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Homo sapiens
-
MDA-MB-231 cell
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Homo sapiens
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MDA-MB-468 cell lowest protein expression Homo sapiens
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additional information DU4475 cell, highest protein expression Homo sapiens
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additional information Hs 578T cell Homo sapiens
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additional information ZR-75-1 cell Homo sapiens
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SK-BR-3 cell lowest protein expression Homo sapiens
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T-47D cell
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Homo sapiens
-

Synonyms

Synonyms Comment Organism
mPGES-1
-
Homo sapiens
prostaglandin E2 synthase-I
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Homo sapiens