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Literature summary for 5.3.99.2 extracted from

  • Ragolia, L.; Hall, C.E.; Palaia, T.
    Lipocalin-type prostaglandin D(2) synthase stimulates glucose transport via enhanced GLUT4 translocation (2008), Prostaglandins Other Lipid Mediat., 87, 34-41.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information adipocytes from lipocalin-type prostaglandin synthase-D knockout mice are significantly less sensitive to insulin-stimulated glucose transport than wild-type Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus lipocalin-type prostaglandin synthase-D can stimulate glucose transport approximately 2fold as well as enhance insulin-stimulated glucose transport due to stimulation of insulin-responsive glucose transporter GLUT4 translocation to the plasma membrane. In response to lipocalin-type prostaglandin synthase-D, there is an increase in GLUT1 expression and an increase in hexokinase III expression ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
adipocyte
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Mus musculus
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L-6 myoblast cell
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Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information lipocalin-type prostaglandin synthase-D can stimulate glucose transport approximately 2fold as well as enhance insulin-stimulated glucose transport due to stimulation of insulin-responsive glucose transporter GLUT4 translocation to the plasma membrane. In response to lipocalin-type prostaglandin synthase-D, there is an increase in GLUT1 expression and an increase in hexokinase III expression Rattus norvegicus ?
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