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Literature summary for 5.3.4.1 extracted from

  • Fernandes, M.M.; Gomes, A.C.; Vasconcelos, A.; Munteanu, F.D.; Tzanov, T.; Goncalves, M.S.; End, N.; Schoening, K.U.; Guebitz, G.M.; Cavaco-Paulo, A.
    Protein disulphide isomerase-assisted functionalization of keratin-based matrices (2011), Appl. Microbiol. Biotechnol., 90, 1311-1321.
    View publication on PubMed

Application

Application Comment Organism
industry PDI assists incorporation of cysteine-containing compounds (CCCs) into hair and wool substrates in order to generate milder methods to dye hair with longer lasting colour by creating new disulfide bonds between hair and peptide. PDI-assists promotion of the migration of CCCs (dyes), previously attached to keratin, along hair fibres, to avoid repetitive hair dyeing procedures. PDI induces controlled release of a CCC protein (e.g. reduced form of RNase A) from wool matrices Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PDI catalyzes the isomerization of disulfide bonds on misfolded proteins Bos taurus ?
-
?
additional information study on the interaction of disulfide dyes 2-[(2,4-dinitrophenyl)amino]-3-sulfanylpropanoic acid and 8-[[7,12-diammonio-2-(1H-imidazo[2,1-c][1,2,4]benzotriazin-10-ium-8-yl)-6,13-dioxo-5,14-dioxa-9,10-dithia-2-azahexadecan-16-yl](methyl)amino]-1H-imidazo[2,1-c][1,2,4]benzotriazin-10-ium Bos taurus ?
-
?
RNase A
-
Bos taurus ?
-
?
TAMRAX3CX4CX2-CONH2
-
Bos taurus ?
-
?

Synonyms

Synonyms Comment Organism
PDI
-
Bos taurus
Protein disulphide isomerase
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Bos taurus