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Literature summary for 5.3.4.1 extracted from

  • Mandel, R.; Ryser, H.J.P.; Ghani, F.; Wu, M.; Peak, D.
    Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase (1993), Proc. Natl. Acad. Sci. USA, 90, 4112-4116.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum lumen Bos taurus 5783
-
endoplasmic reticulum surface-associated Bos taurus 5783
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Proteins Bos taurus catalyzes disulfide cleavage in membrane-bound diphtheria toxin or the membrane-bound conjugate, iodotyramine conjugated with poly(D-Lys) via a 3,3'-dithiobis(propionic acid) spacer ?
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
calf
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Insulin-(SS) + GSH
-
Bos taurus Insulin-(SH)2 + GSSG
-
?
Proteins native, reduced or with wrong disulfide bonds Bos taurus Proteins with correct disulfide bonds ?
Proteins catalyzes disulfide cleavage in membrane-bound diphtheria toxin or the membrane-bound conjugate, iodotyramine conjugated with poly(D-Lys) via a 3,3'-dithiobis(propionic acid) spacer Bos taurus ?
-
?