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Literature summary for 5.3.3.2 extracted from

  • Ghimire, G.P.; Lee, H.C.; Sohng, J.K.
    Improved squalene production via modulation of the methylerythritol 4-phosphate pathway and heterologous expression of genes from Streptomyces peucetius ATCC 27952 in Escherichia coli (2009), Appl. Environ. Microbiol., 75, 7291-7293.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
industry over-expression of isopentenyl diphosphate isomerase and 1-deoxy-D-xylulose 5-phosphate synthase in combination with heterologous expression of squalene/phytoene synthase and farnesyl diphosphate synthase of Streptomyces peucetius in Escherichia coli facilitates the synthesis of the industrially important compound squalene Escherichia coli

Cloned(Commentary)

Cloned (Comment) Organism
for expression in Escherichia coli BL21DE3 cells Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isopentenyl diphosphate Escherichia coli
-
dimethylallyl diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isopentenyl diphosphate
-
Escherichia coli dimethylallyl diphosphate
-
?

Synonyms

Synonyms Comment Organism
isopentenyl diphosphate isomerase
-
Escherichia coli