Literature summary for 5.3.3.12 extracted from

Rosengren, E.; Rorsman, H.
Reducing compounds initiate the TRP2-catalyzed conversion of L-dopachrome to DHICA (1998), Melanoma Res., 8, 469-470.

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Activating Compound

Activating Compound	Comment	Organism	Structure
L-ascorbic acid	enzyme activity depends on the presence of a reducing compound to a final concentration of 0.1mM	Mus musculus
L-cysteine	enzyme activity depends on the presence of a reducing compound to a final concentration of 0.1mM	Mus musculus
additional information	no stimulation by D-dopachrome	Mus musculus
N-acetyl-L-cysteine	enzyme activity depends on the presence of a reducing compound to a final concentration of 0.1mM	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Mus musculus	16020	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
melanoma cell	B16 melanoma	Mus musculus	-

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Release 2023.1 (January 2023)