Organic Solvent | Comment | Organism |
---|---|---|
guanidine-HCl | dissociation/unfolding is a highly cooperative transition in which the ternary and the secondary structures of the protein are concomitantly lost. Isolation of two conformational isomers of the enzyme that exhibit significantly different stabilities and kinetics of unfolding | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Renatured (Comment) | Organism |
---|---|
two conformational isomers of the enzyme that exhibit significantly different stabilities and kinetics of unfolding. Complete unfolding of the two isolated conformers at a 1.5 M guanidine-HCl followed by refolding by removal of the denaturant completely abolishes the differences in their unfolding kinetics | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
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