Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of genes ef2898, ef0685, and ef1534 deletion mutants | Enterococcus faecalis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | enzymes EF0685 and EF1534 | Enterococcus faecalis | 9986 | - |
intracellular | enzyme EF2898 | Enterococcus faecalis | 5622 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Enterococcus faecalis | Q82ZZ9 | gene ef2898 | - |
Enterococcus faecalis | Q834U8 | gene ef1534 | - |
Enterococcus faecalis | Q837Y9 | gene ef0685 | - |
Synonyms | Comment | Organism |
---|---|---|
EF0685 | - |
Enterococcus faecalis |
EF1534 | - |
Enterococcus faecalis |
EF2898 | - |
Enterococcus faecalis |
peptidylprolyl cis/trans isomerase | - |
Enterococcus faecalis |
PPIase | - |
Enterococcus faecalis |
General Information | Comment | Organism |
---|---|---|
malfunction | a DELTAef0685/DELTAef1534 mutant is more resistant to oxidative stress, is able to grow under a high manganese concentration, and shows altered resistance to ampicillin and quinolone antibiotics | Enterococcus faecalis |
additional information | EF0685, EF1534, and EF2898 protein sequence comparisons, overview | Enterococcus faecalis |
physiological function | peptidylprolyl cis/trans isomerases are enzymes involved in protein folding. The parvulin family rotamase EF0685 and the cyclophilin family member EF1534 are important for virulence and resistance to NaCl, while EF2898 is not important for the Enterococcus faecalis stress response or virulence | Enterococcus faecalis |