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Literature summary for 5.2.1.8 extracted from

  • Fujiyama-Nakamura, S.; Yoshikawa, H.; Homma, K.; Hayano, T.; Tsujimura-Takahashi, T.; Izumikawa, K.; Ishikawa, H.; Miyazawa, N.; Yanagida, M.; Miura, Y.; Shinkawa, T.; Yamauchi, Y.; Isobe, T.; Takahashi, N.
    Parvulin (Par14), a peptidyl-prolyl cis-trans isomerase, is a novel rRNA processing factor that evolved in the metazoan lineage (2009), Mol. Cell. Proteomics, 8, 1552-1565.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.2.1.8

Cloned(Commentary)

Cloned (Comment) Organism
Par14, sequence comparisons, expression of GST-tagged enzyme in Escherichia coli Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information Par14 knockout leads to suppression of cell growth, phenotype, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Mus musculus 5737
-
cytoplasm
-
 Homo sapiens 5737
-
additional information co-localizing with the nucleolar-specific protein B23 in quiescent cells, Par14 localizes to the nucleolus of those cells during interphase, and Par14 co-localized almost completely with B23 in the spindle apparatus during mitosis Mus musculus
-
-
additional information co-localizing with the nucleolar-specific protein B23 in quiescent cells, Par14 localizes to the nucleolus of those cells during interphase, and Par14 co-localized almost completely with B23 in the spindle apparatus during mitosis Homo sapiens
-
-
nucleus endogenous Par14 is present in nuclear Pre-40 S and Pre-60 S ribosomal fractions Mus musculus 5634
-
nucleus endogenous Par14 is present in nuclear Pre-40 S and Pre-60 S ribosomal fractions Homo sapiens 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
14000
-
 x * 14000, about, SDS-PAGE Mus musculus
14000
-
 x * 14000, about, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus Par14 behaves as a component of the preribosomal ribonucleoprotein, pre-rRNP, complexes in vivo interacting via its residues 36-41, proteomics analysis of the Par14-associated pre-rRNP complexes, overview ?
-
 ?
additional information Homo sapiens Par14 behaves as a component of the preribosomal ribonucleoprotein, pre-rRNP, complexes in vivo interacting via its residues 36-41, proteomics analysis of the Par14-associated pre-rRNP complexes, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant GST-tagged enzyme from Escherichia coli Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
 Homo sapiens
-
HEK-293-EBNA cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-
L-929 cell a fibroblast cell line Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information Par14 behaves as a component of the preribosomal ribonucleoprotein, pre-rRNP, complexes in vivo interacting via its residues 36-41, proteomics analysis of the Par14-associated pre-rRNP complexes, overview Mus musculus ?
-
 ?
additional information Par14 behaves as a component of the preribosomal ribonucleoprotein, pre-rRNP, complexes in vivo interacting via its residues 36-41, proteomics analysis of the Par14-associated pre-rRNP complexes, overview Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 14000, about, SDS-PAGE Mus musculus
? x * 14000, about, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
Par14
-
 Mus musculus
Par14
-
 Homo sapiens
Parvulin
-
 Mus musculus
Parvulin
-
 Homo sapiens
Peptidyl-prolyl cis-trans isomerase
-
 Mus musculus
Peptidyl-prolyl cis-trans isomerase
-
 Homo sapiens
PPIase
-
 Mus musculus
PPIase
-
 Homo sapiens