Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.2.1.8 extracted from

  • Peloponese, J.M.; Yasunaga, J.; Kinjo, T.; Watashi, K.; Jeang, K.T.
    Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB (2009), J. Virol., 83, 3238-3248.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.2.1.8

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens Pin1 interacts with human T-cell leukemia virus type 1 Tax, phosphorylated at Ser258, and modulates its activation of NF-kappaB. Pin1 contributes to Tax signaling through NF-kappaB, and it cooperates with Tax to enhance cellular proliferation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Homo sapiens
-
H9 cell
-
 Homo sapiens
-
JURKAT cell
-
 Homo sapiens
-
T-lymphocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information Pin1 interacts with human T-cell leukemia virus type 1 Tax, phosphorylated at Ser258, and modulates its activation of NF-kappaB. Pin1 contributes to Tax signaling through NF-kappaB, and it cooperates with Tax to enhance cellular proliferation Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
peptidylproline cis-trans-isomerase
-
 Homo sapiens
Pin1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens Pin1 expression is enhanced in transformed T-cell lines C8166-45, MT4, and JPX9 expressing oncoprotein Tax from human T-cell leukemia virus type 1 up