Protein Variants | Comment | Organism |
---|---|---|
S19A | mutation abolishes phosphorylation and alters the subcellular localization from predominantly nuclear to significantly cytoplasmic | Homo sapiens |
S19E | mutant enzyme is localized around the nuclear envelope, but does not penetrate into the nucleoplasm, in vitro DNA-binding affinity is strongly reduced | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | bound to double-stranded DNA. The subcellular localization is regulated by posttranslational modification of its N-terminal domain | Homo sapiens | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | folding helper enzyme that plays a role in cell-cycle and chromatin remodeling | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | phosphorylated at Ser19 in vivo and in vitro. In human HeLa cells the protein is most likely modified by casein kinase 2 | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | folding helper enzyme that plays a role in cell-cycle and chromatin remodeling | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
h Par14 | - |
Homo sapiens |
parvulin1 4 | - |
Homo sapiens |