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Literature summary for 5.2.1.8 extracted from

  • Bergsma, D.J.; Eder, C.; Gross, M.; Kersten, H.; Sylvester, D.; Appelbaum, E.; Cusimano, D.; Livi, G.P.; McLaughlin, M.M.; Kasyan, K.; Porter, T.G.; Silverman, C.; Dunnington, D.; Hand, A.; Prichett, W.P.; Bossard, M.J.; Brandt, M.; Levy, M.A.
    The cyclophilin multigene family of peptidyl-prolyl isomerases. Characterization of three separate human isoforms (1991), J. Biol. Chem., 266, 23204-23214.
    View publication on PubMed
Search for more literature for 5.2.1.8

Cloned(Commentary)

Cloned (Comment) Organism
3 isoforms expressed in Escherichia coli Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
cyclosporin A and analogs Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol isoform CyP1 Homo sapiens 5829
-
membrane and/or organelles, isoforms CyP2 and CyP3 Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
3 isoforms: CyP1, CyP2, CyP3 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
T-lymphocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information substrate specificity of the 3 isoforms Homo sapiens ?
-
 ?
succinyl-Ala-Ala-Pro-Phe 4-nitroanilide
-
 Homo sapiens succinyl-Ala-Ala-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Glu-(cis)-Pro-Phe 4-nitroanilide
-
 Homo sapiens Succinyl-Ala-Glu-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Gly-(cis)-Pro-Phe 4-nitroanilide
-
 Homo sapiens Succinyl-Ala-Gly-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Leu-(cis)-Pro-Phe 4-nitroanilide
-
 Homo sapiens Succinyl-Ala-Leu-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Lys-(cis)-Pro-Phe 4-nitroanilide
-
 Homo sapiens Succinyl-Ala-Lys-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Phe-(cis)-Pro-Phe 4-nitroanilide
-
 Homo sapiens Succinyl-Ala-Phe-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Val-(cis)-Pro-Phe 4-nitroanilide
-
 Homo sapiens Succinyl-Ala-Val-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Arg-Leu-(cis)-Pro-Phe 4-nitroanilide
-
 Homo sapiens Succinyl-Arg-Leu-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Leu-Leu-(cis)-Pro-Phe 4-nitroanilide
-
 Homo sapiens Succinyl-Leu-Leu-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Phe-Leu-(cis)-Pro-Phe 4-nitroanilide
-
 Homo sapiens Succinyl-Phe-Leu-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ser-Leu-(cis)-Pro-Phe 4-nitroanilide
-
 Homo sapiens Succinyl-Ser-Leu-(trans)-Pro-Phe 4-nitroanilide
-
 ?