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Literature summary for 5.2.1.8 extracted from

  • Huss, R.
    Inhibition of cyclophilin function in HIV-I infection by cyclosporin A (1996), Trends Immunol., 17, 259-260.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
cyclosporin A the combination of cyclosporin A or its analogues with other drugs, such as nucleotide analogues, e.g. 3'-azido-3'-deoxy-thymidine, or 2',3'-dideoxycytidine, HIV-1-protease inhibitors, and antibiotics, might provide long-term benefit to HIV-1-infected individuals Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the presence of cyclophilin A in the human immunodeficiency virus type 1, HIV-1, is required for HIV-1 to infect and replicate ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the presence of cyclophilin A in the human immunodeficiency virus type 1, HIV-1, is required for HIV-1 to infect and replicate Homo sapiens ?
-
?