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Literature summary for 5.1.99.4 extracted from

  • Sattar, F.A.; Darley, D.J.; Politano, F.; Woodman, T.J.; Threadgill, M.D.; Lloyd, M.D.
    Unexpected stereoselective exchange of straight-chain fatty acyl-CoA alpha-protons by human alpha-methylacyl-CoA racemase 1A (P504S) (2010), Chem. Commun. (Camb. ), 46, 3348-3350.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
decanoyl-CoA non-competitive substrate inhibition at higher substrate concentrations Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.614
-
(S)-2-methyldecanoyl-CoA pH and temperature not specified in the publication Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-2-methyldecanoyl-CoA
-
Homo sapiens (S)-2-methyldecanoyl-CoA
-
r
(S)-2-methyldecanoyl-CoA
-
Homo sapiens (R)-2-methyldecanoyl-CoA
-
r

Synonyms

Synonyms Comment Organism
alpha-methylacyl-CoA racemase 1A
-
Homo sapiens
AMACR
-
Homo sapiens
P504S
-
Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.07
-
(S)-2-methyldecanoyl-CoA pH and temperature not specified in the publication Homo sapiens

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
0.114
-
(S)-2-methyldecanoyl-CoA pH and temperature not specified in the publication Homo sapiens