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Literature summary for 5.1.99.4 extracted from

  • Daugherty, S.E.; Shugart, Y.Y.; Platz, E.A.; Fallin, M.D.; Isaacs, W.B.; Pfeiffer, R.M.; Welch, R.; Huang, W.Y.; Reding, D.; Hayes, R.B.
    Polymorphic variants in alpha-methylacyl-CoA racemase and prostate cancer (2007), Prostate, 67, 1487-1497.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
genotyping, determination of five non-synonymous and two intronic AMACR polymorphisms, no associations between the genetic variants and prostate cancer, overview Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Ibuprofen chemopreventive effects of ibuprofen on prostate cancer risk, which may be enhanced by AMACR genetic variants Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme prepares branched chain fatty acids to be metabolized for energy and is implicated in the activation of the COX-inhibiting form of ibuprofen ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
prostate cancer cell enzyme overexpression in prostate cancer and its precursor lesions, differences in AMACR allele frequencies, overview Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme prepares branched chain fatty acids to be metabolized for energy and is implicated in the activation of the COX-inhibiting form of ibuprofen Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
alpha-methylacyl-CoA racemase
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Homo sapiens
AMACR
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Homo sapiens