Crystallization (Comment) | Organism |
---|---|
mutant Y265F in complex with D- and with L-cycloserine | Geobacillus stearothermophilus |
Protein Variants | Comment | Organism |
---|---|---|
Y265F | 1600fold reduction of racemization | Geobacillus stearothermophilus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-cycloserine | model for inactivation mechanism via geminal diamine and ketimine to isoxazole | Geobacillus stearothermophilus | |
L-Cycloserine | model for inactivation mechanism via geminal diamine and ketimine to isoxazole | Geobacillus stearothermophilus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Geobacillus stearothermophilus | P10724 | - |
- |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.33 | - |
D-cycloserine | mutant Y265F, 37°C, pH 9.1 | Geobacillus stearothermophilus | |
4 | - |
D-cycloserine | or higher, wild-type, 37°C, pH 9.1 | Geobacillus stearothermophilus | |
6 | - |
L-Cycloserine | wild-type, 37°C, pH 9.1 | Geobacillus stearothermophilus |